GNG4
Guanine nucleotide binding protein (G protein), gamma 4 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | GNG4 ; DKFZp547K1018; FLJ23803; FLJ34187 | ||||||||||||
External IDs | OMIM: 604388 MGI: 102703 HomoloGene: 3299 GeneCards: GNG4 Gene | ||||||||||||
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RNA expression pattern | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 2786 | 14706 | |||||||||||
Ensembl | ENSG00000168243 | ENSMUSG00000021303 | |||||||||||
UniProt | P50150 | P50153 | |||||||||||
RefSeq (mRNA) | NM_001098721 | NM_010317 | |||||||||||
RefSeq (protein) | NP_001092191 | NP_034447 | |||||||||||
Location (UCSC) | Chr 1: 235.71 – 235.81 Mb | Chr 13: 13.78 – 13.83 Mb | |||||||||||
PubMed search | |||||||||||||
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 is a protein that in humans is encoded by the GNG4 gene.[1][2]
Interactions
GNG4 has been shown to sometimes interact with GNB1.[1][3]
References
- ↑ 1.0 1.1 Ray K, Kunsch C, Bonner LM, Robishaw JD (Oct 1995). "Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits". J. Biol. Chem. 270 (37): 21765–71. doi:10.1074/jbc.270.37.21765. PMID 7665596.
- ↑ "Entrez Gene: GNG4 guanine nucleotide binding protein (G protein), gamma 4".
- ↑ Yan K, Kalyanaraman V, Gautam N (Mar 1996). "Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families". J. Biol. Chem. 271 (12): 7141–6. doi:10.1074/jbc.271.12.7141. PMID 8636150.
Further reading
- Downes GB, Gautam N (1999). "The G protein subunit gene families". Genomics 62 (3): 544–52. doi:10.1006/geno.1999.5992. PMID 10644457.
- Pumiglia KM, LeVine H, Haske T, Habib T, Jove R, Decker SJ (1995). "A direct interaction between G-protein beta gamma subunits and the Raf-1 protein kinase". J. Biol. Chem. 270 (24): 14251–4. doi:10.1074/jbc.270.24.14251. PMID 7782277.
- Yan K, Kalyanaraman V, Gautam N (1996). "Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families". J. Biol. Chem. 271 (12): 7141–6. doi:10.1074/jbc.271.12.7141. PMID 8636150.
- Cuello F, Schulze RA, Heemeyer F, Meyer HE, Lutz S, Jakobs KH et al. (2003). "Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta". J. Biol. Chem. 278 (9): 7220–6. doi:10.1074/jbc.M210304200. PMID 12486123.
- Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.