GNG13

Guanine nucleotide binding protein (G protein), gamma 13
Identifiers
SymbolsGNG13 ; G(gamma)13; h2-35
External IDsOMIM: 607298 HomoloGene: 81890 GeneCards: GNG13 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez5176464337
EnsemblENSG00000127588ENSMUSG00000025739
UniProtQ9P2W3Q9JMF3
RefSeq (mRNA)NM_016541NM_022422
RefSeq (protein)NP_057625NP_071867
Location (UCSC)Chr 16:
0.85 – 0.85 Mb
Chr 17:
25.72 – 25.72 Mb
PubMed search

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 is a protein that in humans is encoded by the GNG13 gene.[1][2]

Interactions

GNG13 has been shown to interact with GNB5.[3]

References

  1. Huang L, Shanker YG, Dubauskaite J, Zheng JZ, Yan W, Rosenzweig S et al. (Jan 2000). "Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium". Nat Neurosci 2 (12): 1055–62. doi:10.1038/15981. PMID 10570481.
  2. "Entrez Gene: GNG13 guanine nucleotide binding protein (G protein), gamma 13".
  3. Blake BL, Wing MR, Zhou JY, Lei Q, Hillmann JR, Behe CI et al. (Dec 2001). "G beta association and effector interaction selectivities of the divergent G gamma subunit G gamma(13)". J. Biol. Chem. 276 (52): 49267–74. doi:10.1074/jbc.M106565200. PMID 11675383.

Further reading

  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Daniels RJ, Peden JF, Lloyd C, Horsley SW, Clark K, Tufarelli C et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.". Hum. Mol. Genet. 10 (4): 339–52. doi:10.1093/hmg/10.4.339. PMID 11157797.
  • Blake BL, Wing MR, Zhou JY, Lei Q, Hillmann JR, Behe CI et al. (2002). "G beta association and effector interaction selectivities of the divergent G gamma subunit G gamma(13).". J. Biol. Chem. 276 (52): 49267–74. doi:10.1074/jbc.M106565200. PMID 11675383.
  • Huang L, Max M, Margolskee RF, Su H, Masland RH, Euler T (2003). "G protein subunit G gamma 13 is coexpressed with G alpha o, G beta 3, and G beta 4 in retinal ON bipolar cells.". J. Comp. Neurol. 455 (1): 1–10. doi:10.1002/cne.10396. PMID 12454992.
  • Cuello F, Schulze RA, Heemeyer F, Meyer HE, Lutz S, Jakobs KH et al. (2003). "Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.". J. Biol. Chem. 278 (9): 7220–6. doi:10.1074/jbc.M210304200. PMID 12486123.
  • Kato C, Mizutani T, Tamaki H, Kumagai H, Kamiya T, Hirobe A et al. (2004). "Characterization of heterotrimeric G protein complexes in rice plasma membrane.". Plant J. 38 (2): 320–31. doi:10.1111/j.1365-313X.2004.02046.x. PMID 15078334.
  • Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Li Z, Benard O, Margolskee RF (2006). "Ggamma13 interacts with PDZ domain-containing proteins.". J. Biol. Chem. 281 (16): 11066–73. doi:10.1074/jbc.M600113200. PMID 16473877.