GLRA2
| Glycine receptor, alpha 2 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | GLRA2 ; GLR | ||||||||||||
| External IDs | OMIM: 305990 MGI: 95748 HomoloGene: 31070 IUPHAR: 424 ChEMBL: 5871 GeneCards: GLRA2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 2742 | 237213 | |||||||||||
| Ensembl | ENSG00000101958 | ENSMUSG00000018589 | |||||||||||
| UniProt | P23416 | Q7TNC8 | |||||||||||
| RefSeq (mRNA) | NM_001118885 | NM_183427 | |||||||||||
| RefSeq (protein) | NP_001112357 | NP_906272 | |||||||||||
| Location (UCSC) | Chr X: 14.55 – 14.75 Mb | Chr X: 165.13 – 165.33 Mb | |||||||||||
| PubMed search | |||||||||||||
Glycine receptor subunit alpha-2 is a protein that in humans is encoded by the GLRA2 gene.[1]
See also
References
Further reading
- Grenningloh G, Schmieden V, Schofield PR et al. (1990). "Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.". EMBO J. 9 (3): 771–6. PMC 551735. PMID 2155780.
- Monani U, Burghes AH (1997). "Structure of the human alpha 2 subunit gene of the glycine receptor--use of vectorette and Alu-exon PCR.". Genome Res. 6 (12): 1200–6. doi:10.1101/gr.6.12.1200. PMID 8973915.
- Cummings CJ, Dahle EJ, Zoghbi HY (1998). "Analysis of the genomic structure of the human glycine receptor alpha2 subunit gene and exclusion of this gene as a candidate for Rett syndrome.". Am. J. Med. Genet. 78 (2): 176–8. doi:10.1002/(SICI)1096-8628(19980630)78:2<176::AID-AJMG16>3.0.CO;2-K. PMID 9674912.
- Feng J, Craddock N, Jones IR et al. (2001). "Systematic screening for mutations in the glycine receptor alpha2 subunit gene (GLRA2) in patients with schizophrenia and other psychiatric diseases.". Psychiatr. Genet. 11 (1): 45–8. doi:10.1097/00041444-200103000-00009. PMID 11409700.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Davies DL, Crawford DK, Trudell JR et al. (2004). "Multiple sites of ethanol action in alpha1 and alpha2 glycine receptors suggested by sensitivity to pressure antagonism.". J. Neurochem. 89 (5): 1175–85. doi:10.1111/j.1471-4159.2004.02390.x. PMID 15147510.
- Miller PS, Harvey RJ, Smart TG (2005). "Differential agonist sensitivity of glycine receptor alpha2 subunit splice variants.". Br. J. Pharmacol. 143 (1): 19–26. doi:10.1038/sj.bjp.0705875. PMC 1575261. PMID 15302677.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Miller PS, Da Silva HM, Smart TG (2006). "Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors.". J. Biol. Chem. 280 (45): 37877–84. doi:10.1074/jbc.M508303200. PMID 16144831.
External links
- GLRA2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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