GJD4
| Gap junction protein, delta 4, 40.1kDa | |||||||||||
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| Identifiers | |||||||||||
| Symbols | GJD4 ; CX40.1; RP11-425A6.2 | ||||||||||
| External IDs | OMIM: 611922 MGI: 2444990 HomoloGene: 17692 IUPHAR: 727 GeneCards: GJD4 Gene | ||||||||||
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| Orthologs | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | 219770 | 225152 | |||||||||
| Ensembl | ENSG00000177291 | ENSMUSG00000036855 | |||||||||
| UniProt | Q96KN9 | Q8BSD4 | |||||||||
| RefSeq (mRNA) | NM_153368 | NM_153086 | |||||||||
| RefSeq (protein) | NP_699199 | NP_694726 | |||||||||
| Location (UCSC) | Chr 10: 35.89 – 35.9 Mb | Chr 18: 9.28 – 9.28 Mb | |||||||||
| PubMed search | |||||||||||
Gap junction delta-4 protein (GJD4), also known as connexin-40.1 (Cx40.1), is a protein that in humans is encoded by the GJD4 gene.[1]
Function
Connexins, such as GJD4, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[1][2]
References
- ↑ 1.0 1.1 "Entrez Gene: gap junction protein".
- ↑ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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