GINS2
| GINS complex subunit 2 (Psf2 homolog) | |||||||||||||
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 PDB rendering based on 2e9x. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | GINS2 ; HSPC037; PSF2; Pfs2 | ||||||||||||
| External IDs | OMIM: 610609 HomoloGene: 41105 GeneCards: GINS2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 51659 | 272551 | |||||||||||
| Ensembl | ENSG00000131153 | ENSMUSG00000031821 | |||||||||||
| UniProt | Q9Y248 | Q9D600 | |||||||||||
| RefSeq (mRNA) | NM_016095 | NM_178856 | |||||||||||
| RefSeq (protein) | NP_057179 | NP_849187 | |||||||||||
| Location (UCSC) | Chr 16: 85.68 – 85.69 Mb | Chr 8: 120.58 – 120.59 Mb | |||||||||||
| PubMed search | |||||||||||||
DNA replication complex GINS protein PSF2 is a protein that in humans is encoded by the GINS2 gene.[1][2][3]
Interactions
GINS2 has been shown to interact with CHEK2.[4]
References
- ↑ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ et al. (Nov 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
- ↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
- ↑ "Entrez Gene: GINS2 GINS complex subunit 2 (Psf2 homolog)".
- ↑ Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER, Hurov KE, Luo J et al. (May 2007). "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage". Science 316 (5828): 1160–6. doi:10.1126/science.1140321. PMID 17525332.
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Takayama Y, Kamimura Y, Okawa M, Muramatsu S, Sugino A, Araki H (2003). "GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast". Genes Dev. 17 (9): 1153–65. doi:10.1101/gad.1065903. PMC 196052. PMID 12730134.
- Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER, Hurov KE, Luo J et al. (2007). "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage". Science 316 (5828): 1160–6. doi:10.1126/science.1140321. PMID 17525332.
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