G3BP2

GTPase activating protein (SH3 domain) binding protein 2
Identifiers
SymbolG3BP2
External IDsMGI: 2442040 HomoloGene: 137244 GeneCards: G3BP2 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez990823881
EnsemblENSG00000138757ENSMUSG00000029405
UniProtQ9UN86P97379
RefSeq (mRNA)NM_012297NM_001080794
RefSeq (protein)NP_036429NP_001074263
Location (UCSC)Chr 4:
76.57 – 76.65 Mb
Chr 5:
92.05 – 92.08 Mb
PubMed search

Ras GTPase-activating protein-binding protein 2 is an enzyme that in humans is encoded by the G3BP2 gene.[1][2][3]

Interactions

G3BP2 has been shown to interact with IκBα.[4]

References

  1. Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (December 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
  2. Kennedy D, Wood SA, Ramsdale T, Tam PP, Steiner KA, Mattick JS (June 1998). "Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif". Biomed Pept Proteins Nucleic Acids 2 (3): 93–9. PMID 9575347.
  3. "Entrez Gene: G3BP2 GTPase activating protein (SH3 domain) binding protein 2".
  4. Prigent, M; Barlat I; Langen H; Dargemont C (November 2000). "IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2". J. Biol. Chem. (UNITED STATES) 275 (46): 36441–9. doi:10.1074/jbc.M004751200. ISSN 0021-9258. PMID 10969074.

Further reading