Fentiazac

Fentiazac
Systematic (IUPAC) name

2-[4-(4-chlorophenyl)-2-phenyl-1,3-thiazol-5-yl]acetic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Registry Number	18046-21-4
ATC code	M02AA14
PubChem	CID 28871
UNII	0YHF6E6NLS^Y
KEGG	D01975^Y
Chemical data
Formula	C₁₇H₁₂Cl N O₂S
Molecular mass	329.80068 g/mol
Physical data
Melting point	162–163 °C (324–325 °F)
Y (what is this?) (verify)

Fentiazac is a nonsteroidal antiinflammatory agent used for joint and muscular pain.

Synthesis

Thiobenzamide is reacted with 3-(4-chlorobenzoyl)-3-bromopropionic acid:

Synthesis of Fentiazac:^[1]

↑ Brown, K.; Cater, D. P.; Cavalla, J. F.; Green, D.; Newberry, R. A.; Wilson, A. B. (1974). "Nonsteroidal antiinflammatory agents. 1. 2,4-Diphenylthiazole-5-acetic acid and related compounds". Journal of Medicinal Chemistry 17 (11): 1177–1181. doi:10.1021/jm00257a010. PMID 4414839.

Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)

Acetic acid derivatives
and related substances

Propionic acid derivatives
(profens)

N-Arylanthranilic acids
(fenamates)

Other

Items listed in bold indicate initially developed compounds of specific groups. ^#WHO-EM ^†Withdrawn drugs. ^‡Veterinary use medications.

Index of muscle

Description	Anatomy head neck arms chest and back diaphragm abdomen genital area legs Muscle tissue Physiology connective tissue

Disease	Myopathy Soft tissue Connective tissue Congenital abdomen muscular dystrophy Neoplasms and cancer Injury Symptoms and signs eponymous

Treatment	Procedures Drugs anti-inflammatory muscle relaxants

Topical products for joint and muscular pain (M02)

Anti-inflammatory
preparations,
non-steroids

Pyrazolidines	Phenylbutazone Mofebutazone Clofezone Oxyphenbutazone

Acetic acid derivatives	Tolmetin Diclofenac Fentiazac

Other	Benzydamine Etofenamate Piroxicam Felbinac Bufexamac Ketoprofen Bendazac Naproxen Ibuprofen Feprazone Niflumic acid Meclofenamic acid Flurbiprofen Suxibuzone Indometacin Nifenazone

Capsaicin derivatives

Other

Index of joint

Description	Anatomy head and neck cranial arms torso and pelvis legs bursae and sheathes Physiology

Disease	Arthritis acquired back childhood soft tissue Congenital Injury Symptoms and signs eponymous orthopaedic Examination

Treatment	Procedures Drugs rheumatoid arthritis gout topical analgesics