Fenbufen

Fenbufen

Systematic (IUPAC) name
4-(4-Biphenylyl)-4-oxobutanoic acid or 4-Oxo-4-(4-phenylphenyl)butanoic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	POM
Routes of administration	Oral
Identifiers
CAS Registry Number	36330-85-5
ATC code	M01AE05
PubChem	CID 3335
DrugBank	DB08981 Y
ChemSpider	3218 Y
UNII	9815R1WR9B Y
KEGG	D01344 Y
ChEBI	CHEBI:31599 Y
ChEMBL	CHEMBL277522 Y
Chemical data
Formula	C16H14O3
Molecular mass	254.2854
SMILES O=C(O)CCC(=O)c2ccc(c1ccccc1)cc2
InChI InChI=1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19)  Y Key:ZPAKPRAICRBAOD-UHFFFAOYSA-N  Y
Y (what is this?)  (verify)

Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by preventing cyclooxygenase from producing prostaglandins which can cause inflammation.

Synthesis

Fenbufen synthesis.^[1]

References