Farletuzumab

Farletuzumab?
Monoclonal antibody
Type Whole antibody
Source Humanized
Target FR-alpha
Clinical data
Identifiers
896723-44-7 
None
UNII 2O09BG0OWA Yes
KEGG D09343 Yes
Chemical data
Formula C6466H9928N1716O2020S42
145.4 kDa
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Farletuzumab (MORAb-003) is a monoclonal antibody[1] which is being investigated for the treatment of ovarian cancer.[2][3]

This drug was developed by Morphotek, Inc.

It is targeted at FR-alpha which is overexpressed in some cancers such as ovarian cancer.

References

  1. Statement On A Nonproprietary Name Adopted By The Usan Council - Farletuzumab, American Medical Association.
  2. ClinicalTrials.gov: Phase II Efficacy and Safety Study of MORAb-003 in Platinum-Resistant or Refractory Relapsed Ovarian Cancer
  3. ClinicalTrials.gov: Phase III Efficacy and Safety of MORAb-003 in Subjects With Platinum-sensitive Ovarian Cancer in First Relapse