Ezlopitant
Ezlopitant (CJ-11,974) is an NK1 receptor antagonist.[1][2][3] It has antiemetic and antinociceptive effects.[4][5] Pfizer was developing ezlopitant for the treatment of irritable bowel syndrome but it appears to have been discontinued.[1]
See also
References
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| Drugs for functional bowel disorders | | Tertiary amino group | |
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| Quaternary ammonium compounds | |
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| Belladonna and derivatives (antimuscarinics) | |
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| Propulsives | |
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| Description |
- Anatomy
- Physiology
- Development
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| Disease |
- Congenital
- Neoplasms and cancer
- Inflammatory bowel disease
- Gluten sensitivity
- Other
- Symptoms and signs
- Blood tests
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| Treatment |
- Procedures
- Drugs
- anabolic steroids
- antacids
- diarrhoea and infection
- bile and liver
- functional gastrointestinal disorders
- laxatives
- peptic ulcer and reflux
- nausea and vomiting
- other
- Surgery
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| CGRP | |
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| Cholecystokinin | |
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| CRH | |
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| Galanin | |
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| MCH | | |
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- Agonists: Melanin concentrating hormone
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| Melanocortin | | |
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| Unsorted |
- Agonists: Alsactide
- Codactide
- Giractide
- Norleusactide
- Seractide
- Tosactide
- Tricosactide
- Tridecactide
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| Neuropeptide S | |
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| Neuropeptide Y | |
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| Neurotensin | |
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| Opioid | See here instead. |
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| Orexin | |
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| Oxytocin | |
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| Tachykinin | |
- Agonists: Substance P
Antagonists: Aprepitant
- Befetupitant
- Burapitant
- Casopitant
- CI-1021
- CP-96,345
- CP-99,994
- CP-122,721
- Dapitant
- Ezlopitant
- Figopitant
- FK-888
- Fosaprepitant
- GR-203,040
- GW-597,599
- HSP-117
- L-733,060
- L-741,671
- L-743,310
- L-758,298
- Lanepitant
- LY-306,740
- Maropitant
- Netupitant
- NKP-608
- Nolpitantium besilate
- Orvepitant
- Rolapitant
- RP-67,580
- SDZ NKT 343
- Serlopitant
- Telmapitant
- Vestipitant
- Vofopitant
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| Vasopressin | |
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| See also: Peptidergics |
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