Ethadione

Ethadione
Systematic (IUPAC) name

3-ethyl-5,5-dimethyl-1,3-oxazolidine-2,4-dione
Clinical data
Identifiers
CAS Registry Number	520-77-4^Y
ATC code	N03AC03
PubChem	CID 10630
ChemSpider	10184^Y
UNII	I0F8O700BB^Y
KEGG	C17724^Y
ChEMBL	CHEMBL93047^Y
Chemical data
Formula	C₇H₁₁N O₃
Molecular mass	157.167 g/mol
SMILES O=C1N(C(=O)OC1(C)C)CC
InChI InChI=1S/C7H11NO3/c1-4-8-5(9)7(2,3)11-6(8)10/h4H2,1-3H3 ^Y Key:SIGSNYAYBSJATD-UHFFFAOYSA-N ^Y
Y (what is this?) (verify)

Not to be confused with ethanedione or ethenedione.

Ethadione is an anticonvulsant medication in the oxazolidinedione family used mainly to treat seizures.^[1]

References

↑ Bergstrand, A.; Bergstrand, C. G.; Engstrom, N.; Herrlin, K. M. (1962). "Renal histology during treatment with oxazolidine-diones (trimethadione, ethadione, and paramethadione)". Pediatrics 30: 601–607. PMID 13970793.

Anticonvulsants (N03)

GABA_AR PAMs	Barbiturates: Barbexaclone Metharbital Methylphenobarbital Pentobarbital Phenobarbital^# Primidone; Carbamates: Felbamate; Benzodiazepines: Clobazam Clonazepam Clorazepate Diazepam^# Lorazepam^# Midazolam Nimetazepam Nitrazepam Temazepam; Others: Bromide (potassium bromide, sodium bromide) Paraldehyde Stiripentol

GABA-T inhibitors	Fatty acids: Valproic acid^# (sodium valproate, valproate semisodium) Valpromide Valproate pivoxil; Others: Ethanolamine-O-sulfate Vigabatrin

Others	GABAR agonists: Progabide; GAT-1 inhibitors: Tiagabine

Channelergics

Sodium blockers	Hydantoins: Ethotoin Fosphenytoin Mephenytoin Phenytoin^#; Ureas: Phenacemide Pheneturide; Fatty acids: Valproic acid^# (sodium valproate, valproate semisodium) Valpromide Valproate pivoxil; Carboxamides: Carbamazepine^# Eslicarbazepine acetate Oxcarbazepine; Others: Lacosamide Lamotrigine Rufinamide Topiramate Zonisamide

Calcium blockers	Oxazolidinediones: Ethadione Paramethadione Trimethadione; Succinimides: Ethosuximide^# Mesuximide Phensuximide; Gabapentinoids: Gabapentin Pregabalin; Others: Lamotrigine Topiramate Zonisamide

Potassium openers	Retigabine

Others

CA inhibitors	Sulfonamides: Acetazolamide Ethoxzolamide Sultiame Topiramate Zonisamide

Others	Beclamide Levetiracetam Perampanel

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Index of psychology and psychiatry

Description	Mental processes

Disorders	Mental and behavioral ADHD OCD Tourette's Mood Developmental pervasive dyslexia and specific Substance-related alcohol Emotional and behavioral Symptoms and signs eponymous Evaluation and testing

Treatment	Psychotherapy CBT Drugs depression antipsychotics anxiety dementia hypnotics and sedatives psychostimulants, ADHD and nootropics