Estratetraenol

Estratetraenol
Systematic (IUPAC) name
(8S,9S,13R,14S)-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-ol
Clinical data
Identifiers
1150-90-9 Yes
None
PubChem CID 101988
Chemical data
Formula C18H22O
254.366 g/mol
 Yes (what is this?)  (verify)

Estratetraenol, also known as estra-1,3,5(10),16-tetraen-3-ol, is a chemical compound produced by women[1] that has been described as having pheromone-like activities in primates,[2] including humans.[3][4][5][6] It is derivative of the sex hormone estradiol, an estrogen, yet has no known estrogenic effects.

References

  1. ↑ Thysen, B; Elliott, WH; Katzman, PA (1968). "Identification of estra-1,3,5(10),16-tetraen-3-ol (estratetraenol) from the urine of pregnant women (1)". Steroids 11 (1): 73–87. doi:10.1016/S0039-128X(68)80052-2. PMID 4295975.
  2. ↑ Laska, M; Wieser, A; Salazar, LT (2006). "Sex-specific differences in olfactory sensitivity for putative human pheromones in nonhuman primates". Journal of comparative psychology (Washington, D.C. : 1983) 120 (2): 106–12. doi:10.1037/0735-7036.120.2.106. PMID 16719588.
  3. ↑ Jacob, S; Hayreh, DJ; McClintock, MK (2001). "Context-dependent effects of steroid chemosignals on human physiology and mood". Physiology & behavior 74 (1–2): 15–27. doi:10.1016/S0031-9384(01)00537-6. PMID 11564447.
  4. ↑ Savic, I; Berglund, H; Gulyas, B; Roland, P (2001). "Smelling of odorous sex hormone-like compounds causes sex-differentiated hypothalamic activations in humans". Neuron 31 (4): 661–8. doi:10.1016/S0896-6273(01)00390-7. PMID 11545724.
  5. ↑ Berglund, H; Lindström, P; Savic, I (2006). "Brain response to putative pheromones in lesbian women". Proceedings of the National Academy of Sciences of the United States of America 103 (21): 8269–74. doi:10.1073/pnas.0600331103. PMC 1570103. PMID 16705035.
  6. ↑ Berglund, H; Lindström, P; Dhejne-Helmy, C; Savic, I (2008). "Male-to-female transsexuals show sex-atypical hypothalamus activation when smelling odorous steroids". Cerebral cortex (New York, N.Y. : 1991) 18 (8): 1900–8. doi:10.1093/cercor/bhm216. PMID 18056697.

See also