Eptazocine
 | |
| Systematic (IUPAC) name | |
|---|---|
| (1S,6S)-1,4-dimethyl-2,3,4,5,6,7-hexahydro-1H-1,6-methano-4-benzazonin-10-ol | |
| Clinical data | |
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| Oral | |
| Identifiers | |
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72522-13-5 72150-17-5 (bromide) | |
| None | |
| PubChem | CID 3042090 |
| ChemSpider | 2305268 |
| UNII | 2208ZLI77S |
| Chemical data | |
| Formula | C15H21NO |
| 231.333 g/mol | |
|
SMILES
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Eptazocine (Sedapain) is an opioid analgesic which was introduced in Japan by Morishita in 1987.[1][2][3][4] It acts as a mixed κ-opioid receptor agonist and μ-opioid receptor antagonist.[4][5][6]
See also
References
- ↑ Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 396. ISBN 978-3-88763-075-1. Retrieved 29 November 2011.
- ↑ American Chemical Society. Division of Medicinal Chemistry (1990). Annual Reports in Medicinal Chemistry. Academic Press. p. 381. ISBN 978-0-12-040525-1. Retrieved 29 November 2011.
- ↑ Nabeshima T, Matsuno K, Kamei H, Kameyama T (May 1985). "The interaction of eptazocine, a novel analgesic, with opioid receptors". Research Communications in Chemical Pathology and Pharmacology 48 (2): 173–81. PMID 2992058.
- ↑ 4.0 4.1 Hiroshi Nagase; Silvia N. Calderon (21 January 2011). Chemistry of Opioids. Springer. p. 280. ISBN 978-3-642-18106-1. Retrieved 29 November 2011.
- ↑ Tamura T, Ogawa J, Taniguchi T, Waki I (January 1990). "[Preferential action of eptazocine, a novel analgesic, with opioid receptors in isolated guinea pig ileum and mouse vas deferens preparations]". Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica (in Japanese) 95 (1): 41–6. doi:10.1254/fpj.95.1_41. PMID 2154395.
- ↑ Dr. Ian Morton; Ian K. M. Morton; Judith M. Hall; Dr. Judith Hall (1999). Concise dictionary of pharmacological agents: properties and synonyms. Springer. p. 113. ISBN 978-0-7514-0499-9. Retrieved 29 November 2011.
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