Epomediol
Epomediol|
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| Systematic (IUPAC) name |
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(1s,4r,6R,7S)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane-6,7-diol |
| Clinical data |
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| Identifiers |
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56084-15-2 |
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A05BA05 |
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| PubChem |
CID 115056 |
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| ChemSpider |
102967 |
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| Synonyms |
1,3,3-Trimethyl-2-oxabicyclo [2.2.2]octane-6,7-endo,endo-diol |
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| Chemical data |
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| Formula |
C10H18O3 |
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186.248 g/mol |
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SMILES
- OC1CC2C(OC1(C)C(O)C2)(C)C
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Epomediol (trade name Clesidren) is a synthetic terpenoid with choleretic effects. It has been used in the symptomatic treatment of itching due to intrahepatic cholestasis of pregnancy.[1][2][3]
References
- ↑ Gonzalez MC, Iglesias J, Tiribelli C et al. (September 1992). "Epomediol ameliorates pruritus in patients with intrahepatic cholestasis of pregnancy". J Hepatol 16 (1-2): 241–2. doi:10.1016/S0168-8278(05)80122-9. PMID 1484159.
- ↑ Reyes H (December 1992). "The spectrum of liver and gastrointestinal disease seen in cholestasis of pregnancy". Gastroenterol Clin North Am 21 (4): 905–21. PMID 1478743.
- ↑ Reyes H, Simon FR (August 1993). "Intrahepatic cholestasis of pregnancy: an estrogen-related disease". Semin Liver Dis 13 (3): 289–301. doi:10.1055/s-2007-1007357. PMID 8235718.
Bile and liver therapy ( A05) |
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| | Bile therapy | |
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| | Liver therapy | |
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| | Description |
- Anatomy
- Physiology
- Development
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| | Disease |
- Congenital
- Neoplasms and cancer
- Inflammatory bowel disease
- Gluten sensitivity
- Other
- Symptoms and signs
- Blood tests
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| | Treatment |
- Procedures
- Drugs
- anabolic steroids
- antacids
- diarrhoea and infection
- bile and liver
- functional gastrointestinal disorders
- laxatives
- peptic ulcer and reflux
- nausea and vomiting
- other
- Surgery
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