Enteroaggregative Escherichia coli

Enteroaggregative Escherichia coli causes bacteria to stack up on each other, therefore aggregating and colonizing the intestinal mucosa, release enterotoxin and cytotoxins that are used to destroy the cell. A transcription factor named AggR is part of the AraC family transcription activator may regulate some of the virulence factor for EAEC. Several other toxins such as ShET1 (Shigella enterotoxin 1) might also participate in the secretory diarrhea process.[1]

References

  1. ↑ Harrington, S.M., E.G. Dudley, and J.P. Nataro, Pathogenesis of enteroaggregative Escherichia coli infection. FEMS Microbiol Lett, 2006. 254(1): p. 12-8.