Enkurin
| Enkurin, TRPC channel interacting protein | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | ENKUR ; C10orf63 | ||||||||||
| External IDs | OMIM: 611025 MGI: 1918483 HomoloGene: 17022 GeneCards: ENKUR Gene | ||||||||||
| |||||||||||
| Orthologs | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | 219670 | 71233 | |||||||||
| Ensembl | ENSG00000151023 | ENSMUSG00000026679 | |||||||||
| UniProt | Q8TC29 | Q6SP97 | |||||||||
| RefSeq (mRNA) | NM_001270383 | NM_027728 | |||||||||
| RefSeq (protein) | NP_001257312 | NP_082004 | |||||||||
| Location (UCSC) | Chr 10: 25.27 – 25.31 Mb | Chr 2: 21.18 – 21.21 Mb | |||||||||
| PubMed search | |||||||||||
Enkurin is a protein that in humans is encoded by the ENKUR gene.[1][2]
Enkurin interacts with transient receptor potential canonical (TRPC) cation channels (e.g., TRPC1) and functions as an adaptor protein, tethering signal transduction proteins to TRPC channels.[2]
References
- ↑ "Entrez Gene: enkurin".
- ↑ 2.0 2.1 Sutton KA, Jungnickel MK, Wang Y, Cullen K, Lambert S, Florman HM (October 2004). "Enkurin is a novel calmodulin and TRPC channel binding protein in sperm". Dev. Biol. 274 (2): 426–35. doi:10.1016/j.ydbio.2004.07.031. PMID 15385169.
Further reading
- Beech DJ (2007). "Canonical transient receptor potential 5.". Handb Exp Pharmacol (179): 109–23. doi:10.1007/978-3-540-34891-7_6. PMID 17217053.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.