Elephantiasis nostras
Elephantiasis nostras is a cutaneous condition, a final hypertrophic fibrosis following longstanding chronic lymphangitis.[1]:261
Symptoms
The disease usually affects the lower legs or scrotum.[2] The swelling is accompanied by rough nodules or wart-like plaques on the skin. If the disease is not treated, it eventually results in pain and immobility.[3]
Causes
Although elephantiasis nostras resembles the elephantiasis caused by helminths, it is not a filarial disease. Instead, it is a complication of chronic lymphedema.[2] Both elephantiasis nostras and filarial elephantiasis are characterized by impaired lymphatic drainage, which results in excess fluid accumulation.[3]
Treatment
Treatment consists of antibiotics, elevation of the affected limb, and compression. For persons with elephantiasis nostras who are overweight or obese, weight loss is recommended.[3] Oral retinoids have been used to treat the cutaneous manifestations of the disease.[2]
See also
- Chronic lymphangitis
- Elephantiasis
- Skin lesion
- List of cutaneous conditions
References
- ↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ↑ 2.0 2.1 2.2 Lin P, Phillips T. "Vascular Disorders: Ulcers." (2003). In Bolognia JL, Jorizzo JL, Rapini RP (Eds.), Dermatology, p. 1637. Mosby ISBN 0-323-02409-2
- ↑ 3.0 3.1 3.2 Scheinfeld NS. (2009). "Skin Disorders in Older Adults: Vascular, Lymphatic, and Purpuric Dermatitides, Part 2". Consultant 49 (7)