EIF3F

Eukaryotic translation initiation factor 3, subunit F
Identifiers
SymbolsEIF3F ; EIF3S5; eIF3-p47
External IDsOMIM: 603914 MGI: 1913335 HomoloGene: 2783 GeneCards: EIF3F Gene
EC number3.4.19.12
Orthologs
SpeciesHumanMouse
Entrez866566085
EnsemblENSG00000175390ENSMUSG00000031029
UniProtO00303Q9DCH4
RefSeq (mRNA)NM_003754NM_025344
RefSeq (protein)NP_003745NP_079620
Location (UCSC)Chr 11:
7.99 – 8.02 Mb
Chr 7:
108.93 – 108.94 Mb
PubMed search

Eukaryotic translation initiation factor 3 subunit F is a protein that in humans is encoded by the EIF3F gene.[1][2]

Interactions

EIF3F has been shown to interact with Mammalian target of rapamycin[3] and EIF3A.[4][5][6]

References

  1. Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW (Nov 1997). "Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly". J. Biol. Chem. 272 (43): 27042–52. doi:10.1074/jbc.272.43.27042. PMID 9341143.
  2. "Entrez Gene: EIF3S5 eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa".
  3. Harris TE, Chi A, Shabanowitz J, Hunt DF, Rhoads RE, Lawrence JC (Apr 2006). "mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin". EMBO J. 25 (8): 1659–68. doi:10.1038/sj.emboj.7601047. PMC 1440840. PMID 16541103.
  4. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  5. Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (Oct 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.
  6. Block KL, Vornlocher HP, Hershey JW (Nov 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". J. Biol. Chem. 273 (48): 31901–8. doi:10.1074/jbc.273.48.31901. PMID 9822659.

Further reading