Drug carrier
Drug carriers are substances that serve as mechanisms to improve the delivery and the effectiveness of drugs. Drug carriers are used in sundry drug delivery systems such as:
- controlled-release technology to prolong in vivo drug actions;
- decrease drug metabolism, and
- reduce drug toxicity.
Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions.
Examples
Carriers which are able to biodegrade include:
- Liposomes;
- Microspheres made of the biodegradable polymer poly(lactic-co-glycolic) acid
- albumin microspheres;
- synthetic polymers (soluble);
- nanofibers;[1]
- Protein-DNA complexes;
- protein conjugates;
- erythrocytes
- virosomes
- Dendrimers
See also
Resources
The following research papers from IUPAC are in pdf format:
- Biodegradable hydrogels for bone regeneration through growth factor release
- Development of acid-sensitive copolymer micelles for drug delivery
References
- ↑ Nagy ZK; Balogh A; Vajna B; Farkas A; Patyi G; Kramarics A; Marosi G (2011). "Comparison of Electrospun and Extruded Soluplus-Based Solid Dosage Forms of Improved Dissolution". Journal of Pharmaceutical Sciences 101 (1): 322–32. doi:10.1002/jps.22731. PMID 21918982.
External links
- Weighting cancer drugs to make them hit tumors harder PhysOrg.com article
- Designing Better Cancer Drugs Provides insight into carrier molecules' functionality which may yield safer cancer treatments.