Diphenylmethylpiperazine

Diphenylmethylpiperazine

Names
IUPAC name 1-(diphenylmethyl)piperazine
Other names 1-benzhydrylpiperazine
Identifiers
CAS Registry Number	841-77-0
ChemSpider	63238
InChI InChI=1S/C17H20N2/c1-3-7-15(8-4-1)17(16-9-5-2-6-10-16)19-13-11-18-12-14-19/h1-10,17-18H,11-14H2
Jmol-3D images	Image
PubChem	70048
SMILES c1c(cccc1)C(c2ccccc2)N3CCNCC3
Properties
Chemical formula	C17H20N2
Molar mass	252.35 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

1-(Diphenylmethyl)piperazine, also known as benzhydrylpiperazine, is a chemical compound and piperazine derivative. It features a piperazine ring with a benzhydryl (diphenylmethyl) group bound to one of the nitrogens.

A number of diphenylmethylpiperazine derivatives are drugs, including:

• Pharmaceuticals
  • Almitrine - Respiratory stimulant
  • Buclizine - Antihistamine
  • Cetirizine - Antihistamine
  • Chlorcyclizine - Antihistamine
  • Cinnarizine - Antihistamine
  • Clocinizine - Antihistamine
  • Cyclizine - Antihistamine
  • Dotarizine - Antimigraine
  • Hydroxyzine - Antihistamine
  • Meclozine - Antihistamine
  • Oxatomide - Antihistamine
• Research chemicals
  • BW373U86 - Opioid analgesic
  • DPI-221 - Opioid analgesic
  • DPI-287 - Opioid analgesic
  • DPI-3290 - Opioid analgesic
  • SNC-80 - Opioid analgesic

Amperozide, BRL-15,572, chlorbenzoxamine, DBL-583, GBR-12,935, lidoflazine, and vanoxerine are diphenylalkylpiperazines with extended side chains and/or other modifications.

See also

• Phenylpiperazine
• Pyrimidinylpiperazine
• Benzylpiperazine