Dinoxyline
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| Systematic (IUPAC) name | |
|---|---|
| 8,9-dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline | |
| Clinical data | |
| Identifiers | |
| None | |
| PubChem | CID 9819126 |
| ChemSpider | 7994875 |
| Chemical data | |
| Formula | C15H13NO3 |
| 255.268 | |
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SMILES
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Dinoxyline is a synthetic compound developed for scientific research, which acts as a potent full agonist at all five dopamine receptor subtypes.[1][2][3]
References
- ↑ Grubbs RA, Lewis MM, Owens-Vance C, Gay EA, Jassen AK, Mailman RB, Nichols DE (March 2004). "8,9-dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline (dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms". Bioorganic & Medicinal Chemistry 12 (6): 1403–12. doi:10.1016/j.bmc.2004.01.008. PMID 15018913.
- ↑ Ryman-Rasmussen JP, Nichols DE, Mailman RB (October 2005). "Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists". Molecular Pharmacology 68 (4): 1039–48. doi:10.1124/mol.105.012153. PMID 15985612.
- ↑ Zhang J, Xiong B, Zhen X, Zhang A (March 2009). "Dopamine D1 receptor ligands: where are we now and where are we going". Medicinal Research Reviews 29 (2): 272–94. doi:10.1002/med.20130. PMID 18642350.