Dimazole

Dimazole
Systematic (IUPAC) name

[6-(2-Diethylamino-ethoxy)-benzothiazol-2-yl]-dimethyl-amine
Clinical data
Identifiers
CAS Registry Number	95-27-2
ATC code	D01AE17
PubChem	CID 8708
UNII	2KL01R8ZV1^Y
Chemical data
Formula	C₁₅H₂₃N₃O S
Molecular mass	293.42762
Physical data
Melting point	195 to 204 °C (383 to 399 °F)
Y (what is this?) (verify)

Dimazole (or diamthazole) is an antifungal.^[1]

Synthesis

Diamthazole synthesis: U.S. Patent 2,578,757

References

↑ Drugs.com: diamthazole dihydrochloride

Antifungals (D01 and J02)

Wall/
membrane

Ergosterol
inhibitors

Azoles
(lanosterol 14
alpha-demethylase inhibitors)

Imidazoles	Topical: bifonazole butoconazole clomidazole clotrimazole^#, croconazole econazole fenticonazole ketoconazole isoconazole miconazole^#, neticonazole omoconazole oxiconazole sertaconazole sulconazole tioconazole

Triazoles	Topical: (fluconazole^#, fosfluconazole terconazole) Systemic: (fluconazole hexaconazole isavuconazole^†, itraconazole posaconazole voriconazole) Unknown: (albaconazole)

Thiazoles	Topical: (abafungin)

Polyene antimycotics
(ergosterol binding)

Topical: (hamycin
natamycin
nystatin^#)
Systemic: (amphotericin B^#, hamycin)

Allylamines
(squalene monooxygenase
inhibitors)

Topical: (amorolfine
butenafine
naftifine
terbinafine)
Systemic: terbinafine

β-glucan synthase
inhibitors

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	flucytosine^#

Mitotic inhibitors	griseofulvin^#

Aminoacyl tRNA synthetase inhibitors	tavaborole

Others

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Index of fungal disease

Description	Fungi Classification

Disease	Fungus

Treatment	Drugs