Difluocortolone valerate
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| Names | |
|---|---|
| IUPAC name
(6α,11β,16α)-6,9-Difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl pentanoate | |
| Other names
Afusona; Diflucortolone 21-valerate | |
| Identifiers | |
59198-70-8  | |
| ChEMBL | ChEMBL65702 |
| ChemSpider | 82773 |
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| Jmol-3D images | Image |
| PubChem | 91670 |
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| Properties | |
| Molecular formula |
C27H36F2O5 |
| Molar mass | 478.57 g·mol−1 |
| Melting point | 220 °C (428 °F; 493 K)[1] |
| Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
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| Infobox references | |
Difluocortolone valerate (also Nerisone cream/oily cream/ointment, Neriderm ointment, Japanese ジフルコルトロン (Jifurucorutoron) is a corticosteroid rated Class 2 "potent" (100-150 times) in the New Zealand topical steroid system. It is a white to creamy white crystalline powder. It is practically insoluble in water, freely soluble in dichloromethane and in dioxan, sparingly soluble in ether and slightly soluble in methyl alcohol. Chemically, it is a corticosteroid esterified with valeric acid. It is commonly used topically in dermatology. The brand name is Nerisone; its creams come in potencies of 0.1% and 0.3%.
See also
References
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