Dextranomer

Dextranomer
Systematic (IUPAC) name
Dextran, 2,3-dihydroxypropyl 2-hydroxy-1,3-propanediyl ethers
Clinical data
Trade names Debrisan
AHFS/Drugs.com International Drug Names
Topical
Identifiers
56087-11-7 
D03AX02
PubChem SID214362
Chemical data
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Dextranomer (trade name Debrisan) is a cicatrizant used in dressings for wound healing,[1] and in pharmaceutical products to treat fecal incontinence.[2] It consists of dextran polymer chains cross-linked into a three-dimensional network.[3]

SolestaTM

Solesta is the marketed brand name of a system of injections of dextranomer in stabilized sodium hyaluronate for use in fecal incontinence (FI).[4] This preparation is a biocompatible gel, for use as a perianal injectable bulking agent. The system is intended to be injected in the submucosal layer of the proximal anal canal (i.e. above the level of the dentate line).

References

  1. ↑ Parulkar BG, Sobti MK, Pardanani DS (1985). "Dextranomer dressing in the treatment of infected wounds and cutaneous ulcers". J Postgrad Med 31 (1): 28–33.
  2. ↑ Solesta Gel Approved for Fecal Incontinence
  3. ↑ Solesta Package Insert
  4. ↑ Hoy, SM (Aug 20, 2012). "Dextranomer in stabilized sodium hyaluronate (Solesta®): in adults with faecal incontinence.". Drugs 72 (12): 1671–8. doi:10.2165/11209030-000000000-00000. PMID 22845415.

External links