DCP1B
| Decapping mRNA 1B | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | DCP1B ; DCP1; hDcp1b | ||||||||||||
| External IDs | OMIM: 609843 MGI: 2442404 HomoloGene: 51881 GeneCards: DCP1B Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 196513 | 319618 | |||||||||||
| Ensembl | ENSG00000151065 | ENSMUSG00000041477 | |||||||||||
| UniProt | Q8IZD4 | B9EIX0 | |||||||||||
| RefSeq (mRNA) | NM_152640 | NM_001033379 | |||||||||||
| RefSeq (protein) | NP_689853 | NP_001028551 | |||||||||||
| Location (UCSC) | Chr 12: 2.06 – 2.11 Mb | Chr 6: 119.18 – 119.22 Mb | |||||||||||
| PubMed search | |||||||||||||
mRNA-decapping enzyme 1B is a protein that in humans is encoded by the DCP1B gene.[1][2][3]
DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002).[supplied by OMIM][3]
References
- ↑ Lykke-Andersen J (Nov 2002). "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay". Mol Cell Biol 22 (23): 8114–21. doi:10.1128/MCB.22.23.8114-8121.2002. PMC 134073. PMID 12417715.
- ↑ Cougot N, Babajko S, Seraphin B (Apr 2004). "Cytoplasmic foci are sites of mRNA decay in human cells". J Cell Biol 165 (1): 31–40. doi:10.1083/jcb.200309008. PMC 2172085. PMID 15067023.
- ↑ 3.0 3.1 "Entrez Gene: DCP1B DCP1 decapping enzyme homolog B (S. cerevisiae)".
Further reading
- Beausoleil SA; Villén J; Gerber SA et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
- Rush J; Moritz A; Lee KA et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.
- Gerhard DS; Wagner L; Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
- Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
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