Croconazole

Croconazole
Systematic (IUPAC) name

1-(1-{2-[(3-chlorophenyl)methoxy]phenyl}ethenyl)-1H-imidazole
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	℞ (Prescription only)
Routes of administration	Topical
Identifiers
CAS Registry Number	77175-51-0
ATC code	None
PubChem	CID 2880
ChemSpider	2777
UNII	446254H55G^Y
KEGG	D07752
ChEMBL	CHEMBL27289
Chemical data
Formula	C₁₈H₁₅Cl N₂O
Molecular mass	310.77 g/mol
SMILES Clc1cccc(c1)COc3c(\C(=C)n2ccnc2)cccc3

Croconazole (INN) is an imidazole antifungal.

External links

Antifungals (D01 and J02)

Wall/
membrane

Ergosterol
inhibitors

Azoles
(lanosterol 14
alpha-demethylase inhibitors)

Imidazoles	Topical: bifonazole butoconazole clomidazole clotrimazole^#, croconazole econazole fenticonazole ketoconazole isoconazole miconazole^#, neticonazole omoconazole oxiconazole sertaconazole sulconazole tioconazole

Triazoles	Topical: (fluconazole^#, fosfluconazole terconazole) Systemic: (fluconazole hexaconazole isavuconazole^†, itraconazole posaconazole voriconazole) Unknown: (albaconazole)

Thiazoles	Topical: (abafungin)

Polyene antimycotics
(ergosterol binding)

Topical: (hamycin
natamycin
nystatin^#)
Systemic: (amphotericin B^#, hamycin)

Allylamines
(squalene monooxygenase
inhibitors)

Topical: (amorolfine
butenafine
naftifine
terbinafine)
Systemic: terbinafine

β-glucan synthase
inhibitors

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	flucytosine^#

Mitotic inhibitors	griseofulvin^#

Aminoacyl tRNA synthetase inhibitors	tavaborole

Others

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Index of fungal disease

Description	Fungi Classification

Disease	Fungus

Treatment	Drugs