Corydalis yanhusuo

Corydalis yanhusuo
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
Order: Ranunculales
Family: Papaveraceae
Genus: Corydalis
Species: C. yanhusuo
Binomial name
Corydalis yanhusuo
W.T.Wang

Corydalis yanhusuo is a species of genus Corydalis. Research has indicated that the alkaloid dehydrocorybulbine (DHCB), extracted from the roots of the plant, can be helpful in reducing neuropathic pain.[1][2] Tetrahydropalmatine is a major constituent alkaloid which also has analgesic activity.[3]

Corydalis yanhusuo also contains the alkaloids glaucine[4][5] and palmatine.[6] It also contains the acetylcholinesterase inhibitor corydaline.[7]

N-methyltetrahydroprotoberberines with κ-opioid receptor agonist activity have been isolated from C. yanhusuo.[8]

References

  1. ↑ Chinese herbal compound relieves inflammatory and neuropathic pain
  2. ↑ A Novel Analgesic Isolated from a Traditional Chinese Medicine. Current Biology. Volume 24, Issue 2, p117–123, 20 January 2014
  3. ↑ A Novel Analgesic Isolated from a Traditional Chinese Medicine. Current Biology. Volume 24, Issue 2, p117–123, 20 January 2014
  4. ↑ Xu, XH; Yu, GD; Wang, ZT (2004). "Resource investigation and quality evaluation on wild Corydalis yanhusuo". Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 29 (5): 399–401. PMID 15706885.
  5. ↑ Morteza-Semnani, K; Amin, G; Shidfar, MR; Hadizadeh, H; Shafiee, A (2003). "Antifungal activity of the methanolic extract and alkaloids of Glaucium oxylobum". Fitoterapia 74 (5): 493–6. doi:10.1016/s0367-326x(03)00113-8. PMID 12837370.
  6. ↑ Wang YM, Zhao LB, Lin SL, Dong SS, An DK (1989). "[Determination of berberine and palmatine in cortex phellodendron and Chinese patent medicines by HPLC]". Yao Xue Xue Bao = Acta Pharmaceutica Sinica (in Chinese) 24 (4): 275–9. PMID 2816389.
  7. ↑ Xiao, Hai-Tao; Peng, Jiao; Liang, Yan; Yang, Jie; Bai, Xue; Hao, Xiao-Yan; Yang, Fu-Mei; Sun, Qian-Yun (September 2011). "Acetylcholinesterase inhibitors from Corydalis yanhusuo". Natural Product Research (Taylor and Francis) 25 (15): 1418–1422. doi:10.1080/14786410802496911. ISSN 1478-6419. PMID 20234973. Retrieved September 8, 2013.
  8. ↑ Yan Zhang, Chaoran Wang, Zhimou Guo, Xiuli Zhang, Zhiwei Wang, Xinmiao Liang, Olivier Civelli (2014). "Discovery of N-methyltetrahydroprotoberberines with κ-opioid receptor agonists-opioid receptor agonist activities from corydalis yanhusuo W. T. Wang by using two-dimensional liquid chromatography.". Journal of Ethnopharmacology 155 (3): 1597–1602. doi:10.1016/j.jep.2014.07.057. PMID 25107388.