Coronary perfusion pressure

Coronary perfusion pressure (CPP) refers to the pressure gradient that drives coronary blood pressure, meaning the difference between the diastolic aortic pressure and the left ventricular end-diastolic pressure. It is a term used mainly in research concerning cardiac arrest. In this context, it is assumed that the minimum CPP needed for a successful outcome is 15mm Hg.

CPP is a part of normal blood pressure that is specifically responsible for coronary blood flow. CPP is also, generally, a surrogate term for coronary blood flow.

During cardiac arrest, CPP is one of the most important variables associated with the likelihood of return of spontaneous circulation (ROSC), the restoration of a pulse. A CPP of at least 15 mmHg is thought to be necessary for ROSC.[1]

Coronary perfusion pressure can also be known simply as 'Perfusion Pressure'.

References

  1. ↑ Sutton et al. (August 2014). "Hemodynamic–directed cardiopulmonary resuscitation during in–hospital cardiac arrest". Resuscitation 85 (8): 983–986. doi:10.1016/j.resuscitation.2014.04.015. PMID 24783998.