Colforsin
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Systematic (IUPAC) name | |
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[(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-acetyloxy-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-6-yl] 3-dimethylaminopropanoate | |
Clinical data | |
AHFS/Drugs.com | International Drug Names |
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Identifiers | |
138605-00-2 ![]() | |
None | |
PubChem | CID 444028 |
ChemSpider | 392052 |
UNII |
1F7A44V6OU ![]() |
KEGG |
D01697 ![]() |
ChEMBL | CHEMBL52606 |
Chemical data | |
Formula | C27H43NO8 |
509.631 g/mol | |
SMILES
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Colforsin (INN) is a water-soluble derivative of forskolin.
References
- Mori M, Takeuchi M, Takaoka H, Hata K, Hayashi Y, Yokoyama M (August 1994). "Effect of NKH477, a new water-soluble forskolin derivative, on arterial-ventricular coupling and mechanical energy transduction in patients with left ventricular systolic dysfunction: comparison with dobutamine". J. Cardiovasc. Pharmacol. 24 (2): 310–6. doi:10.1097/00005344-199424020-00018. PMID 7526066.
- Sanbe A, Takeo S (July 1995). "Effects of NKH477, a water-soluble forskolin derivative, on cardiac function in rats with chronic heart failure after myocardial infarction". J. Pharmacol. Exp. Ther. 274 (1): 120–6. PMID 7616388.