Clorexolone

Clorexolone
Systematic (IUPAC) name

6-chloro-2-cyclohexyl-3-oxo-2,3-dihydro- 1H-isoindole-5-sulfonamide
Clinical data
Identifiers
CAS Registry Number	2127-01-7
ATC code	C03BA12
PubChem	CID 16473
ChemSpider	15615
UNII	Q2PLT3FS05^Y
KEGG	D01436
ChEMBL	CHEMBL2106167
Chemical data
Formula	C₁₄H₁₇Cl N₂O₃S
Molecular mass	328.814 g/mol
SMILES O=S(=O)(c1cc2C(=O)N(Cc2cc1Cl)C3CCCCC3)N

Clorexolone is a low-ceiling sulfonamide diuretic.

Antihypertensives: diuretics (C03)

Sulfonamides
(and etacrynic acid)

CA inhibitors (at PT)	Acetazolamide

Loop (Na-K-Cl at AL)	Furosemide^# Bumetanide Etacrynic acid Etozoline Muzolimine Piretanide Tienilic acid Torasemide

Thiazides (Na-Cl at DCT, Calcium-sparing)	Altizide Bendroflumethiazide Chlorothiazide Cyclopenthiazide Cyclothiazide Epithiazide Hydrochlorothiazide^# Hydroflumethiazide Mebutizide Methyclothiazide Polythiazide Trichlormethiazide

Thiazide-likes (primarily DCT)	Quinethazone Clopamide Chlortalidone Mefruside Clofenamide Metolazone Meticrane Xipamide Indapamide Clorexolone Fenquizone

Potassium-sparing (at CD)

ESC blockers	Amiloride^# Triamterene Benzamil

Aldosterone antagonists	Spironolactone^# Eplerenone Potassium canrenoate Canrenone

Osmotic diuretics (PT, DL)

Mannitol^#
Urea

Vasopressin receptor antagonists
(DCT and CD)

tetracyclines: Demeclocycline

Other

ethanol, isopropanol, 2M2B
mercurial diuretic (Mersalyl, Meralluride)
Theobromine
Cicletanine

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Index of the circulatory system

Description	Anatomy Arteries head and neck arms chest abdomen legs Veins head and neck arms chest abdomen and pelvis legs Development Cells Physiology proteins

Disease	Congenital Neoplasms and cancer Lymphatic vessels Injury Vasculitis Other Symptoms and signs eponymous

Treatment	Procedures Drugs beta blockers channel blockers diuretics nonsympatholytic vasodilatory antihypertensives peripheral vasodilators renin–angiotensin system sympatholytic antihypertensives vasoprotectives