Cilofungin
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Names | |
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IUPAC name
N-[(11R,20R,21R,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,21,25-tetrahydroxy-3,15-bis(1-hydroxyethyl)-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.09,13]heptacosan-18-yl]-4-(octyloxy)benzamide | |
Identifiers | |
79404-91-4 ![]() | |
ChEMBL | ChEMBL2103748 ![]() |
ChemSpider | 5293334 ![]() |
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Jmol-3D images | Image |
MeSH | Cilofungin |
PubChem | 6918120 |
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UNII | 8ZJC54A39X ![]() |
Properties | |
Molecular formula |
C49H71N7O17 |
Molar mass | 1,030.12 g·mol−1 |
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
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Infobox references | |
Cilofungin is the first clinically applied member of the Echinocandin family of antifungal drug. It was derived from a fungus in the genus Aspergillus. It accomplishes this by interfering with an invading fungus' ability to synthesize the cell wall (specifically, it inhibits the synthesis of 1,3-beta-D-glucan).[1]
References
- ↑ Hudler, George (1998). Magical Mushrooms, Mischievous Molds. Princeton, New Jersey: Princeton University Press. p. 112. ISBN 978-0-691-07016-2.