Christopher Burge

Chris Burge
Born Christopher Boyce Burge
May 26, 1968[1]
Institutions Massachusetts Institute of Technology
Alma mater Stanford University
Thesis Identification of genes in human genomic DNA (1997)
Doctoral advisor Samuel Karlin[2]
Known for GENSCAN[3][4]
Notable awards Overton Prize[5]
Website
genes.mit.edu/burgelab/cburge.html

Christopher Boyce Burge is the Whitehead Career Development Associate Professor of Biology at Massachusetts Institute of Technology.

Education

Burge completed his Bachelor of Science at Stanford University in 1990, and continued graduate studies in computational biology at Stanford University, gaining his PhD[6] in 1997[1] under the supervision of Samuel Karlin.[3][4] During his time at Stanford he was responsible for developing algorithms for GENSCAN used in gene prediction for example the initial analysis of the Human Genome Project.[7]

Research

From 1997 to 1999 Burge worked as a postdoc in the laboratory of Phillip Allen Sharp.[8] His current research interests include genomics, RNA splicing and microRNA[9] regulation.[10][11][12][13]

Awards

In 2001 he was awarded the Overton Prize[5] for Computational Biology by the International Society for Computational Biology.

References

  1. ↑ 1.0 1.1 http://genes.mit.edu/burgelab/CBurgeCV.pdf Christopher Burge CV
  2. ↑ Christopher Burge at the Mathematics Genealogy Project
  3. ↑ 3.0 3.1 Burge, Christopher; Karlin, Samuel (1997). "Prediction of complete gene structures in human genomic DNA". Journal of Molecular Biology 268 (1): 78–94. doi:10.1006/jmbi.1997.0951. PMID 9149143.
  4. ↑ 4.0 4.1 Burge, C.; Karlin, S. (1998). "Finding the genes in genomic DNA". Current opinion in structural biology 8 (3): 346–354. doi:10.1016/S0959-440X(98)80069-9. PMID 9666331.
  5. ↑ 5.0 5.1 http://www.iscb.org/iscb-awards/overton-prize Overton prize winners
  6. ↑ Burge, Christopher Boyce (2012). Identification of genes in human genomic DNA (PhD thesis). Stanford University.
  7. ↑ Lander, E. S.; Linton, M.; Birren, B.; Nusbaum, C.; Zody, C.; Baldwin, J.; Devon, K.; Dewar, K.; Doyle, M.; Fitzhugh, W.; Funke, R.; Gage, D.; Harris, K.; Heaford, A.; Howland, J.; Kann, L.; Lehoczky, J.; Levine, R.; McEwan, P.; McKernan, K.; Meldrim, J.; Mesirov, J. P.; Miranda, C.; Morris, W.; Naylor, J.; Raymond, C.; Rosetti, M.; Santos, R.; Sheridan, A. et al. (Feb 2001). "Initial sequencing and analysis of the human genome". Nature 409 (6822): 860–921. doi:10.1038/35057062. ISSN 0028-0836. PMID 11237011.
  8. ↑ Burge, C.; Padgett, R.; Sharp, P. (1998). "Evolutionary fates and origins of U12-type introns". Molecular Cell 2 (6): 773–785. doi:10.1016/S1097-2765(00)80292-0. PMID 9885565.
  9. ↑ Rhoades, M. W.; Reinhart, B. J.; Lim, L. P.; Burge, C. B.; Bartel, B.; Bartel, D. P. (2002). "Prediction of Plant MicroRNA Targets". Cell 110 (4): 513–520. doi:10.1016/S0092-8674(02)00863-2. PMID 12202040.
  10. ↑ Christopher Burge's publications indexed by the Scopus bibliographic database, a service provided by Elsevier.
  11. ↑ http://www.biomedexperts.com/Profile.bme/172484/Christopher_B_Burge Chris Burge profile in BiomedExperts
  12. ↑ Lewis, B. P.; Burge, C. B.; Bartel, D. P. (2005). "Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets". Cell 120 (1): 15–20. doi:10.1016/j.cell.2004.12.035. PMID 15652477.
  13. ↑ Lewis, B. P.; Shih, I. H.; Jones-Rhoades, M. W.; Bartel, D. P.; Burge, C. B. (2003). "Prediction of Mammalian MicroRNA Targets". Cell 115 (7): 787–98. doi:10.1016/S0092-8674(03)01018-3. PMID 14697198.