Carboxycyclophosphamide
 | |
| Names | |
|---|---|
| IUPAC name
3-({amino[bis(2-chloroethyl)amino]phosphoryl}oxy)propanoic acid | |
| Other names
Carboxyphosphamide | |
| Identifiers | |
| 22788-18-7 | |
| Jmol-3D images | Image |
| PubChem | 31515 |
| |
| Properties | |
| C7H15Cl2N2O4P | |
| Molar mass | 293.084762 |
| Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
| Infobox references | |
Carboxycyclophosphamide is an inactive metabolite of the cytotoxic antineoplastic drug cyclophosphamide. In the metabolic pathway of cyclophosphamide inactivation it first metabolizes to 4-hydroxycyclophosphamide, then partially tautomerizes into aldophosphamide. Aldophosphamide then, in turn, is oxidized into carboxycyclophosphamide by the enzyme ALDH (aldehyde dehydrogenase).[1]