Cambridge Biomedical Campus

Cambridge Biomedical Campus
Location	Cambridge, United Kingdom
Affiliations	University of Cambridge Cancer Research UK AstraZeneca National Institute for Health Research Wellcome Trust Medical Research Council
Website	cambridge-biomedical.com

The Cambridge Biomedical Campus, located at the southwest end of Hills Road on the southern edge of Cambridge, England, is one of the largest centres of health science and medical research in the world and the largest such centre in Europe.^[1][2] Managed by the University of Cambridge, the site is funded by organisations such as the Cambridge University Hospitals NHS Foundation Trust, the Wellcome Trust, Cancer Research UK, the UK government's Medical Research Council and has National Institute for Health Research Biomedical Research Centre status. It is an accredited UK academic health science centre (Cambridge University Health Partners) and home to Addenbrooke's Hospital and the university's medical school.^[3]

Constituent institutes

The Cambridge Biomedical Campus is home to the following institutes.^[4]

Addenbrooke's Hospital

Addenbrooke's Hospital viewed from the south.

Addenbrooke's Hopital is a large teaching hospital, and the central focus of the campus.

AstraZeneca

AstraZeneca’s global research and development facility is due to be based on the campus^[5] and will house a workforce of approximately 2,000 individuals. It will be home to both early and late-stage medicines discovery and development, and cover both small molecules and biologics. Research activities will span all preclinical functional groups, including antibody engineering, medicinal chemistry and high throughput screening.

University of Cambridge School of Clinical Medicine

The University of Cambridge Medical School, established in 1976.

MRC Laboratory of Molecular Biology

The new building of the Laboratory of Molecular Biology

The LMB is a molecular biology research institute funded by the UK Medical Research Council. It was founded in Cambridge in 1947 as the Unit for Research on the Molecular Structure of Biological Systems and moved to a site adjacent to Addenbrooke's Hospital in 1962. A 27,000m² replacement building close to the previous site was completed in 2012 and opened in May 2013.^[6]

The laboratory has won nine Nobel Prizes including the 1962 prize (Physiology or Medicine) awarded for the discovery of the double-helix structure of DNA.^[7]

Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute

The Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute or 'SCI' is a virtual organisation composed of the Anne McLaren Laboratory for Stem Cell Biology and Regenerative Medicine and the Wellcome Trust Centre for Stem Cell Research, as well as University-based Principal Investigators working in neighbouring Cambridge institutes whose research is primarily focused on stem cell biology and/or translation. The SCI is principally funded by the Wellcome Trust and the Medical Research Council. The Wellcome Trust also funds the SCI's internationally competitive 4-Year PhD Programme in Stem Cell Biology and Medicine. Stem cell biology and regenerative medicine research is a designated University of Cambridge Strategic Initiative.

The aims of the SCI are:

• To make fundamental discoveries that provide new insights into stem cell function and potency;
• To understand the role of stem and progenitor cells in disease and thereby to improve diagnosis and treatment;
• To harness the capacity of endogenous stem and progenitor cells for repair and regeneration;
• To exploit stem cells as tools for studying the molecular pathogenesis of human diseases and discovery of therapeutic agents;
• To nurture future generations of stem cell scientists and clinical investigators in an intellectually invigorating mix of basic and translational research.

The SCI was formed in 2012 following an £8m investment by the Wellcome Trust and the Medical Research Council.^[8] The SCI will eventually be housed in a purpose-built 8000m² facility to be constructed on the Cambridge Biomedical Campus site.

Cancer Research UK Cambridge Institute (Cambridge Cancer Centre)

Li Ka Shing Centre of the Cancer Research UK Cambridge Institute

The Cancer Research UK Cambridge Institute (CRUK-CI) is principally funded by Cancer Research UK and the University of Cambridge^[9] and is a major member institute of the Cambridge Cancer Centre, a virtual organisation of Cambridge researchers whose work has current or potential application to cancer research. The Cambridge Cancer Centre offers highly competitive PhD programmes; both studentships and clinical research training fellowships (for aspiring clinical academics), attracting applicants from the UK and around the world. Cancer research is a designated University of Cambridge Strategic Initiative.

CRUK-CI is home to four main areas of research:

• Basic research, which involves looking into the cellular and molecular biology of cancer.
• Research into molecular imaging, genomics, bioinformatics and biomolecular modeling.
• Research that focuses on specific cancer sites, forming a bridge between the clinical and laboratory areas.
• Clinical investigations and trials, including population based studies into screening and prevention.

The centre was officially opened by Queen Elizabeth II in February 2007.

Cambridge Institute for Medical Research

The Wellcome Trust/MRC building, part of the Biomedical Campus housing the Cambridge Institute for Medical Research and the MRC Mitochondrial Biology Unit

The CIMR is a cross-departmental institute in the University of Cambridge, receiving funding from the Wellcome Trust. Research is focused on four main areas: misfolded proteins and disease, intracellular membrane traffic, autoimmune disease and haematopoietic stem cell biology.^[10]

Wolfson Brain Imaging Centre

The Wolfson Brain Imaging Centre was created in 1995 to develop and apply advanced imaging methods to patients with traumatic brain injury. It is unique in being co-located with the Neurosciences Critical Care Unit of Addenbrooke's Hospital. Since its establishment it has become an internationally leading Positron Emission Tomography and Magnetic Resonance Imaging centre.

Hutchison/MRC Research Centre

The Hutchison/MRC Research Centre is a cancer research centre housing researchers from the University of Cambridge Department of Oncology, the MRC Cancer Cell Unit, and the University of Cambridge "Cambridge Molecular Therapeutics Programme".^[11] The Hutchison/MRC Research Centre is a member institute of the Cambridge Cancer Centre, a virtual organisation of Cambridge researchers whose work has current or potential application to cancer research.

Rosie Maternity Hospital

The Rosie Hospital is Cambridge's first purpose-built maternity hospital, opened in October 1983. A multi-million pound extension of the Rosie Hospital was completed in 2012.

MRC Mitochondrial Biology Unit

The MRC Mitochondrial Biology Unit is funded by the Medical Research Council and is focused on research to understand mitochondrial process and their involvement in human diseases.^[12] It is co-located with the Cambridge Institute for Medical Research in the Wellcome Trust/MRC Building.

Institute of Metabolic Science

The Institute of Metabolic Science (IMS) is dedicated to research, education, prevention and clinical care in the areas of diabetes, obesity and related metabolic and endocrine diseases.^[13]

Brain Repair Centre

Adjacent to the Institute of Public Health, Cambridge Centre for Brain Repair is a subsidiary of the University of Cambridge Department of Clinical Neurosciences. It is a research institute aiming to "understand, and eventually to alleviate and repair damage to the brain and spinal cord which results from injury or neurodegenerative disease."^[14]

Institute for Public Health

The Institute for Public Health is a partnership between the University of Cambridge, the Medical Research Council and the National Health Service. It was created in 1993 to study disease in the population and to identify, evaluate and monitor public healthcare interventions.^[15]

University Technical College Cambridge

The University Technical College Cambridge is a new secondary school for 14-18 year olds offering GCSE, B-Tech and A-Level courses. It opened on the 8th September in the Deakin Centre. On Friday 19th September, it moved into its own building on Robinson Way, situated next to the Long Road Sixth Form College, parallel to the Bio-Medical Campus which encompasses Addenbrooke's Hospital

Other

Other entities located on the Cambridge Biomedical Campus include:

• Institute for Diabetes, Endocrinology and Metabolism
• GlaxoSmithKline Clinical Research Unit
• MRC Centre for Protein Engineering
• National Blood Service
• Strangeways Research Laboratory
• Papworth Hospital is scheduled to relocate to the Cambridge Biomedical Campus in 2017.^[16]

Site map

Below is a map which gives an idea of the scale of the site and the locations of the departments. Research facilities are highlighted in blue, hospital facilities in red and general facilities in green:

Coordinates: 52°10′34″N 0°08′24″E / 52.176°N 0.140°E / 52.176; 0.140

References