CTDSP2
| CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | CTDSP2 ; OS4; PSR2; SCP2 | ||||||||||||
| External IDs | OMIM: 608711 HomoloGene: 128791 GeneCards: CTDSP2 Gene | ||||||||||||
| EC number | 3.1.3.16 | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10106 | 52468 | |||||||||||
| Ensembl | ENSG00000175215 | ENSMUSG00000078429 | |||||||||||
| UniProt | O14595 | Q8BX07 | |||||||||||
| RefSeq (mRNA) | NM_005730 | NM_001113470 | |||||||||||
| RefSeq (protein) | NP_005721 | NP_001106941 | |||||||||||
| Location (UCSC) | Chr 12: 57.82 – 57.85 Mb | Chr 10: 126.98 – 127 Mb | |||||||||||
| PubMed search | |||||||||||||
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 is an enzyme that in humans is encoded by the CTDSP2 gene.[1][2][3]
Interactions
CTDSP2 has been shown to interact with SNAI1.[4]
References
- ↑ Su YA, Lee MM, Hutter CM, Meltzer PS (Oct 1997). "Characterization of a highly conserved gene (OS4) amplified with CDK4 in human sarcomas". Oncogene 15 (11): 1289–94. doi:10.1038/sj.onc.1201294. PMID 9315096.
- ↑ Yeo M, Lin PS, Dahmus ME, Gill GN (Jul 2003). "A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5". J Biol Chem 278 (28): 26078–85. doi:10.1074/jbc.M301791200. PMID 12721286.
- ↑ "Entrez Gene: CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2".
- ↑ Wu, Yadi; Evers B Mark; Zhou Binhua P (Jan 2009). "Small C-terminal domain phosphatase enhances snail activity through dephosphorylation". J. Biol. Chem. (United States) 284 (1): 640–8. doi:10.1074/jbc.M806916200. ISSN 0021-9258. PMC 2610500. PMID 19004823.
Further reading
- Su YA, Trent JM, Guan XY, Meltzer PS (1994). "Direct isolation of genes encoded within a homogeneously staining region by chromosome microdissection.". Proc. Natl. Acad. Sci. U.S.A. 91 (19): 9121–5. doi:10.1073/pnas.91.19.9121. PMC 44759. PMID 8090779.
- Beutler E, Gelbart T, West C et al. (1996). "A strategy for cloning the hereditary hemochromatosis gene.". Blood Cells Mol. Dis. 21 (3): 207–16. doi:10.1006/bcmd.1995.0024. PMID 8673473.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Brandenberger R, Wei H, Zhang S et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Kimura K, Wakamatsu A, Suzuki Y et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Thompson J, Lepikhova T, Teixido-Travesa N et al. (2006). "Small carboxyl-terminal domain phosphatase 2 attenuates androgen-dependent transcription.". EMBO J. 25 (12): 2757–67. doi:10.1038/sj.emboj.7601161. PMC 1500849. PMID 16724108.
External links
- CTDSP2 human gene location in the UCSC Genome Browser.
- CTDSP2 human gene details in the UCSC Genome Browser.