CTDSP1
| CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | |||||||||||||
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 PDB rendering based on 1t9z. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | CTDSP1 ; NIF3; NLI-IF; NLIIF; SCP1 | ||||||||||||
| External IDs | OMIM: 605323 MGI: 2654470 HomoloGene: 100834 ChEMBL: 1795098 GeneCards: CTDSP1 Gene | ||||||||||||
| EC number | 3.1.3.16 | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 58190 | 227292 | |||||||||||
| Ensembl | ENSG00000144579 | ENSMUSG00000026176 | |||||||||||
| UniProt | Q9GZU7 | P58466 | |||||||||||
| RefSeq (mRNA) | NM_001206878 | NM_153088 | |||||||||||
| RefSeq (protein) | NP_001193807 | NP_694728 | |||||||||||
| Location (UCSC) | Chr 2: 219.26 – 219.27 Mb | Chr 1: 74.39 – 74.4 Mb | |||||||||||
| PubMed search | |||||||||||||
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 is an enzyme that in humans is encoded by the CTDSP1 gene.[1][2][3]
Interactions
CTDSP1 has been shown to interact with SNAI1.[4]
References
- ↑ Ma X, Wright J, Dou S, Olsen P, Teeter L, Adams G, Graviss E (Apr 2002). "Ethnic divergence and linkage disequilibrium of novel SNPs in the human NLI-IF gene: evidence of human origin and lack of association with tuberculosis susceptibility". J Hum Genet 47 (3): 140–5. doi:10.1007/s100380200016. PMID 11950066.
- ↑ Yeo M, Lin PS, Dahmus ME, Gill GN (Jul 2003). "A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5". J Biol Chem 278 (28): 26078–85. doi:10.1074/jbc.M301791200. PMID 12721286.
- ↑ "Entrez Gene: CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1".
- ↑ Wu, Yadi; Evers B Mark; Zhou Binhua P (Jan 2009). "Small C-terminal domain phosphatase enhances snail activity through dephosphorylation". J. Biol. Chem. (United States) 284 (1): 640–8. doi:10.1074/jbc.M806916200. ISSN 0021-9258. PMC 2610500. PMID 19004823.
Further reading
- Marquet S, Lepage P, Hudson TJ et al. (2000). "Complete nucleotide sequence and genomic structure of the human NRAMP1 gene region on chromosome region 2q35.". Mamm. Genome 11 (9): 755–62. doi:10.1007/s003350010151. PMID 10967134.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Fernandes AO, Campagnoni CW, Kampf K et al. (2004). "Identification of a protein that interacts with the golli-myelin basic protein and with nuclear LIM interactor in the nervous system.". J. Neurosci. Res. 75 (4): 461–71. doi:10.1002/jnr.10882. PMID 14743429.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Yeo M, Lee SK, Lee B et al. (2005). "Small CTD phosphatases function in silencing neuronal gene expression.". Science 307 (5709): 596–600. doi:10.1126/science.1100801. PMID 15681389.
- Rual JF, Venkatesan K, Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Sapkota G, Knockaert M, Alarcón C et al. (2007). "Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.". J. Biol. Chem. 281 (52): 40412–9. doi:10.1074/jbc.M610172200. PMID 17085434.
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