CNOT8

CCR4-NOT transcription complex, subunit 8
Identifiers
SymbolsCNOT8 ; CAF1; CALIF; Caf1b; POP2; hCAF1
External IDsOMIM: 603731 MGI: 1916375 HomoloGene: 48304 GeneCards: CNOT8 Gene
EC number3.1.13.4
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez933769125
EnsemblENSG00000155508ENSMUSG00000020515
UniProtQ9UFF9Q9D8X5
RefSeq (mRNA)NM_001301073NM_026949
RefSeq (protein)NP_001288002NP_081225
Location (UCSC)Chr 5:
154.24 – 154.26 Mb
Chr 11:
58.1 – 58.12 Mb
PubMed search

CCR4-NOT transcription complex subunit 8 is a protein that in humans is encoded by the CNOT8 gene.[1][2][3]

Interactions

CNOT8 has been shown to interact with BTG2,[4] BTG1,[4][5] CNOT1[2][6] and CNOT3.[2]

References

  1. Fidler C, Wainscoat JS, Boultwood J (May 1999). "The human POP2 gene: identification, sequencing, and mapping to the critical region of the 5q- syndrome". Genomics 56 (1): 134–6. doi:10.1006/geno.1998.5687. PMID 10036195.
  2. 2.0 2.1 2.2 Albert TK, Lemaire M, van Berkum NL, Gentz R, Collart MA, Timmers HT (March 2000). "Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits". Nucleic Acids Res. 28 (3): 809–17. doi:10.1093/nar/28.3.809. PMC 102560. PMID 10637334.
  3. "Entrez Gene: CNOT8 CCR4-NOT transcription complex, subunit 8".
  4. 4.0 4.1 Prévôt D, Morel AP, Voeltzel T, Rostan MC, Rimokh R, Magaud JP et al. (March 2001). "Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathway". J. Biol. Chem. 276 (13): 9640–8. doi:10.1074/jbc.M008201200. PMID 11136725. Vancouver style error (help)
  5. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  6. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

Further reading