| Weekday programming |
| ET | Program | Retransmitted channel | Hosts | Description |
| 00:00 | Mad Money | CNBC | Jim Cramer | Fast-paced show offering stock advice to callers | Rerun from 18:00 |
| 01:00 | Squawk Box Europe | CNBC World (from CNBC Europe) | Geoff Cutmore | Derived from CNBC's Squawk Box | Live |
| 04:00 | Morning Exchange | CNBC | Ross Westgate, Louisa Bojesen | Derived from CNBC's former Morning Exchange with Liz Claman |
| 05:00 | Wake-Up Call | Brad Goode, Michelle Caruso-Cabrera | First word on futures movement and trading Europe and Asia |
| 07:00 | Squawk Box | Mark Haines, David Faber, Joe Kernen, Steve Liesman, Rebecca Quick | Provides a mix of business news and commentary |
| 10:00 | Morning Call | Ted David, Liz Claman | Focuses on real-time market coverage |
| 12:00 | Power Lunch | Bill Griffeth, Sue Herera | Examines the companies, people, and trends influencing Wall Street |
| 14:00 | Street Signs | Erin Burnett | |
| 15:00 | Closing Bell | Joe Kernen/David Faber, Maria Bartiromo | Covers the close of the trading day |
| 17:00 | Kudlow & Company | Lawrence Kudlow | Provides market and economic commentary and interviews |
| 18:00 | Mad Money | James Cramer | A fast-paced show offering stock advice to callers |
| 19:00 | Late Night with Conan O'Brien | Conan O'Brien | Talk show | Rerun from 00:35 on NBC |
| N/A (EST) / 20:00 (EDT) | Asia Squawk Box | CNBC World (from CNBC Asia) | Martin Soong | Derived from CNBC's Squawk Box | Live |
| 20:00 (EST) / 21:00 (EDT) | Asia Market Watch | Amanda Drury | Derived from CNBC's former Market Watch with Maria Bartiromo |
