CHTF18
| CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | CHTF18 ; C16orf41; C321D2.2; C321D2.3; C321D2.4; CHL12; Ctf18; RUVBL | ||||||||||||
| External IDs | OMIM: 613201 MGI: 2384887 HomoloGene: 32532 GeneCards: CHTF18 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 63922 | 214901 | |||||||||||
| Ensembl | ENSG00000127586 | ENSMUSG00000019214 | |||||||||||
| UniProt | Q8WVB6 | Q8BIW9 | |||||||||||
| RefSeq (mRNA) | NM_022092 | NM_145409 | |||||||||||
| RefSeq (protein) | NP_071375 | NP_663384 | |||||||||||
| Location (UCSC) | Chr 16: 0.84 – 0.85 Mb | Chr 17: 25.72 – 25.73 Mb | |||||||||||
| PubMed search | |||||||||||||
Chromosome transmission fidelity protein 18 homolog is a protein that in humans is encoded by the CHTF18 gene.[1][2]
Interactions
CHTF18 has been shown to interact with DCC1,[3][4] RFC2,[3][4] RFC3,[3][4] PCNA,[1] RFC4[3] and RFC5.[3]
References
- ↑ 1.0 1.1 Ohta S, Shiomi Y, Sugimoto K, Obuse C, Tsurimoto T (Oct 2002). "A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein". J Biol Chem 277 (43): 40362–7. doi:10.1074/jbc.M206194200. PMID 12171929.
- ↑ "Entrez Gene: CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)".
- ↑ 3.0 3.1 3.2 3.3 3.4 Bermudez, Vladimir P; Maniwa Yoshimasa; Tappin Inger; Ozato Keiko; Yokomori Kyoko; Hurwitz Jerard (Sep 2003). "The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA". Proc. Natl. Acad. Sci. U.S.A. (United States) 100 (18): 10237–42. doi:10.1073/pnas.1434308100. ISSN 0027-8424. PMC 193545. PMID 12930902.
- ↑ 4.0 4.1 4.2 Merkle, Carolin J; Karnitz Larry M, Henry-Sánchez John T, Chen Junjie (Aug 2003). "Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment". J. Biol. Chem. (United States) 278 (32): 30051–6. doi:10.1074/jbc.M211591200. ISSN 0021-9258. PMID 12766176.
Further reading
- Shiomi Y, Masutani C, Hanaoka F et al. (2007). "A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase eta activity.". J. Biol. Chem. 282 (29): 20906–14. doi:10.1074/jbc.M610102200. PMID 17545166.
- Beausoleil SA, Jedrychowski M, Schwartz D et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Bermudez VP, Maniwa Y, Tappin I et al. (2003). "The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA.". Proc. Natl. Acad. Sci. U.S.A. 100 (18): 10237–42. doi:10.1073/pnas.1434308100. PMC 193545. PMID 12930902.
- Merkle CJ, Karnitz LM, Henry-Sánchez JT, Chen J (2003). "Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment.". J. Biol. Chem. 278 (32): 30051–6. doi:10.1074/jbc.M211591200. PMID 12766176.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Naiki T, Kondo T, Nakada D et al. (2001). "Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway.". Mol. Cell. Biol. 21 (17): 5838–45. doi:10.1128/MCB.21.17.5838-5845.2001. PMC 87303. PMID 11486023.
- Daniels RJ, Peden JF, Lloyd C et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.". Hum. Mol. Genet. 10 (4): 339–52. doi:10.1093/hmg/10.4.339. PMID 11157797.