CFU-GEMM

CFU-GEMM
Identifiers
Code TH H2.00.04.3.02008
Anatomical terminology

CFU-GEMM is a colony forming unit that generates myeloid cells. CFU-GEMM cells are multipotential progenitor cells.[1][2] "GEMM" stands for granulocyte, erythrocyte, monocyte, megakaryocyte.[3]

CFU-GEMM gives rise to CFU-GM.

It has been suggested that eosinophils do not derive from the common myeloid progenitor in humans.[4]

References

  1. ↑ Carow CE, Hangoc G, Broxmeyer HE (February 1993). "Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: an effect enhanced by cord blood plasma". Blood 81 (4): 942–9. PMID 7679010.
  2. ↑ Roodman GD, LeMaistre CF, Clark GM, Page CP, Newcomb TF, Knight WA (August 1987). "CFU-GEMM correlate with neutrophil and platelet recovery in patients receiving autologous marrow transplantation after high-dose melphalan chemotherapy". Bone Marrow Transplant. 2 (2): 165–73. PMID 3332164.
  3. ↑ "Hem I WBC Morphology and Physiology". Retrieved 2008-12-30.
  4. ↑ Mori Y, Iwasaki H, Kohno K et al. (January 2009). "Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor". J. Exp. Med. 206 (1): 183–93. doi:10.1084/jem.20081756. PMC 2626675. PMID 19114669.