CFHR2
| Complement factor H-related 2 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | CFHR2 ; CFHL2; FHR2; HFL3 | ||||||||||||
| External IDs | OMIM: 600889 HomoloGene: 130536 GeneCards: CFHR2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 3080 | 545366 | |||||||||||
| Ensembl | ENSG00000080910 | ENSMUSG00000033898 | |||||||||||
| UniProt | P36980 | E9Q402 | |||||||||||
| RefSeq (mRNA) | NM_005666 | NM_001025575.2 | |||||||||||
| RefSeq (protein) | NP_005657 | NP_001020746.1 | |||||||||||
| Location (UCSC) | Chr 1: 196.79 – 196.93 Mb | Chr 1: 141.7 – 141.92 Mb | |||||||||||
| PubMed search | |||||||||||||
Complement factor H-related protein 2 is a protein that in humans is encoded by the CFHR2 gene.[1][2][3]
References
- ↑ Skerka C, Timmann C, Horstmann RD, Zipfel PF (Jun 1992). "Two additional human serum proteins structurally related to complement factor H. Evidence for a family of factor H-related genes". J Immunol 148 (10): 3313–8. PMID 1533657.
- ↑ Skerka C, Moulds JM, Taillon-Miller P, Hourcade D, Zipfel PF (Oct 1995). "The human factor H-related gene 2 (FHR2): structure and linkage to the coagulation factor XIIIb gene". Immunogenetics 42 (4): 268–74. doi:10.1007/bf00176444. PMID 7672821.
- ↑ "Entrez Gene: CFHR2 complement factor H-related 2".
Further reading
- Zipfel PF, Skerka C (1994). "Complement factor H and related proteins: an expanding family of complement-regulatory proteins?". Immunol. Today 15 (3): 121–6. doi:10.1016/0167-5699(94)90155-4. PMID 8172644.
- Hageman GS, Hancox LS, Taiber AJ et al. (2007). "Extended Haplotypes in the Complement Factor H (CFH) and CFH-related (CFHR) Family of Genes that Protect against Age-related Macular Degeneration: Identification, Ethnic Distribution and Evolutionary Implications". Ann. Med. 38 (8): 592–604. doi:10.1080/07853890601097030. PMC 1905836. PMID 17438673.
- Gregory SG, Barlow KF, McLay KE et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Díaz-Guillén MA, Rodríguez de Córdoba S, Heine-Suñer D (1999). "A radiation hybrid map of complement factor H and factor H-related genes". Immunogenetics 49 (6): 549–52. doi:10.1007/s002510050534. PMID 10380701.
- Skerka C, Horstmann RD, Zipfel PF (1991). "Molecular cloning of a human serum protein structurally related to complement factor H". J. Biol. Chem. 266 (18): 12015–20. PMID 1711047.