CCDC85B
| Coiled-coil domain containing 85B | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | CCDC85B ; DIPA | ||||||||||||
| External IDs | OMIM: 605360 MGI: 2147607 HomoloGene: 4989 GeneCards: CCDC85B Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 11007 | 240514 | |||||||||||
| Ensembl | ENSG00000175602 | ENSMUSG00000095098 | |||||||||||
| UniProt | Q15834 | Q6PDY0 | |||||||||||
| RefSeq (mRNA) | NM_006848 | NM_001243307 | |||||||||||
| RefSeq (protein) | NP_006839 | NP_001230236 | |||||||||||
| Location (UCSC) | Chr 11: 65.66 – 65.66 Mb | Chr 19: 5.46 – 5.46 Mb | |||||||||||
| PubMed search | |||||||||||||
Coiled-coil domain-containing protein 85B is a protein that in humans is encoded by the CCDC85B gene.[1][2][3]
Hepatitis delta virus (HDV) is a pathogenic human virus whose RNA genome and replication cycle resemble those of plant viroids. Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen (HDAg). DIPA interacts with the viral antigen, HDAg, and can affect HDV replication in vitro.[3]
Interactions
CCDC85B has been shown to interact with KIAA1267,[4] Keratin 17,[4] Protein kinase N1[4] and C19orf25.[4]
References
- ↑ Brazas R, Ganem D (October 1996). "A cellular homolog of hepatitis delta antigen: implications for viral replication and evolution". Science 274 (5284): 90–4. doi:10.1126/science.274.5284.90. PMID 8810253.
- ↑ Bezy O, Elabd C, Cochet O, Petersen RK, Kristiansen K, Dani C, Ailhaud G, Amri EZ (March 2005). "Delta-interacting protein A, a new inhibitory partner of CCAAT/enhancer-binding protein beta, implicated in adipocyte differentiation". J Biol Chem 280 (12): 11432–8. doi:10.1074/jbc.M411741200. PMID 15644333.
- ↑ 3.0 3.1 "Entrez Gene: CCDC85B coiled-coil domain containing 85B".
- ↑ 4.0 4.1 4.2 4.3 Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Further reading
- Robertson HD (1996). "How did replicating and coding RNAs first get together?". Science 274 (5284): 66–7. doi:10.1126/science.274.5284.66. PMID 8848724.
- Long M, de Souza SJ, Gilbert W (1997). "Delta-interacting protein A and the origin of hepatitis delta antigen.". Science 276 (5313): 824–5. doi:10.1126/science.276.5313.824. PMID 9115212.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Schumacher B, Schertel C, Wittenburg N et al. (2005). "C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage.". Cell Death Differ. 12 (2): 153–61. doi:10.1038/sj.cdd.4401539. PMID 15605074.
- Rual JF, Venkatesan K, Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Lim J, Hao T, Shaw C et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
- Du X, Wang Q, Hirohashi Y, Greene MI (2007). "DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription.". Exp. Mol. Pathol. 81 (3): 184–90. doi:10.1016/j.yexmp.2006.07.008. PMID 17014843.