CCDC6
| Coiled-coil domain containing 6 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | CCDC6 ; D10S170; H4; PTC; TPC; TST1 | ||||||||||||
| External IDs | OMIM: 601985 MGI: 1923801 HomoloGene: 34786 GeneCards: CCDC6 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 8030 | 76551 | |||||||||||
| Ensembl | ENSG00000108091 | ENSMUSG00000048701 | |||||||||||
| UniProt | Q16204 | D3YZP9 | |||||||||||
| RefSeq (mRNA) | NM_005436 | NM_001111121 | |||||||||||
| RefSeq (protein) | NP_005427 | NP_001104591 | |||||||||||
| Location (UCSC) | Chr 10: 61.55 – 61.67 Mb | Chr 10: 70.1 – 70.19 Mb | |||||||||||
| PubMed search | |||||||||||||
Coiled-coil domain-containing protein 6 is a protein that in humans is encoded by the CCDC6 gene.[1][2][3]
Interactions
CCDC6 has been shown to interact with PPP4C.[4][5]
References
- ↑ Grieco M, Cerrato A, Santoro M, Fusco A, Melillo RM, Vecchio G (Sep 1994). "Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo". Oncogene 9 (9): 2531–5. PMID 8058316.
- ↑ Anne-Spence M, Falk CT, Neiswanger K, Field LL, Marazita ML, Allen FH et al. (Sep 1984). "Estimating the recombination frequency for the PTC-Kell linkage". Human Genetics 67 (2): 183–6. doi:10.1007/BF00272997. PMID 6745938.
- ↑ "Entrez Gene: CCDC6 coiled-coil domain containing 6".
- ↑ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- ↑ Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M, Gingras AC (Oct 2008). "PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4". The Journal of Biological Chemistry 283 (43): 29273–84. doi:10.1074/jbc.M803443200. PMC 2662017. PMID 18715871.
Further reading
- Sato O (Mar 1976). "[The dynamics of cerebrospinal fluid circulation (author's transl)]". No Shinkei Geka. Neurological Surgery 4 (3): 211–7. PMID 775355.
- Grieco M, Santoro M, Berlingieri MT, Melillo RM, Donghi R, Bongarzone I et al. (Feb 1990). "PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas". Cell 60 (4): 557–63. doi:10.1016/0092-8674(90)90659-3. PMID 2406025.
- Tong Q, Li Y, Smanik PA, Fithian LJ, Xing S, Mazzaferri EL et al. (May 1995). "Characterization of the promoter region and oligomerization domain of H4 (D10S170), a gene frequently rearranged with the ret proto-oncogene". Oncogene 10 (9): 1781–7. PMID 7753554.
- Hillier LD, Lennon G, Becker M, Bonaldo MF, Chiapelli B, Chissoe S et al. (Sep 1996). "Generation and analysis of 280,000 human expressed sequence tags". Genome Research 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549. Check date values in:
|year= / |date= mismatch(help) - Celetti A, Cerrato A, Merolla F, Vitagliano D, Vecchio G, Grieco M (Jan 2004). "H4(D10S170), a gene frequently rearranged with RET in papillary thyroid carcinomas: functional characterization". Oncogene 23 (1): 109–21. doi:10.1038/sj.onc.1206981. PMID 14712216.
- Brill LM, Salomon AR, Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Analytical Chemistry 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
- Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J et al. (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935. Vancouver style error (help)
- Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R et al. (Jan 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (Oct 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. Vancouver style error (help)
- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P et al. (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- Merolla F, Pentimalli F, Pacelli R, Vecchio G, Fusco A, Grieco M et al. (Sep 2007). "Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage". Oncogene 26 (42): 6167–75. doi:10.1038/sj.onc.1210446. PMID 17420723.