CC-1088

CC-1088 is a thalidomide analogue inhibitor of phosphodiesterase 4 that was being developed up to 2005 by Calgene Corp., for treating of inflammatory diseases and myelodysplastic syndromes.[1] CC-10004 was found to be a preferable.[2]

References

  1. ↑ K. Dredge (May 2005). "CC-1088 Celgene". Current Opinion in Investigatoional Drugs 6 (5): 513–7. PMID 15912966.
  2. ↑ Molostvov G, Morris A, Rose P, Basu S, Muller G. (February 2004). "The effects of selective cytokine inhibitory drugs (CC-10004 and CC-1088) on VEGF and IL-6 expression and apoptosis in myeloma and endothelial cell co-cultures". British Journal of Haematology 124 (3): 366–75. doi:10.1046/j.1365-2141.2003.04777.x. PMID 14717786.

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