CBARA1

Mitochondrial calcium uptake 1

Available structures

Ortholog search: PDBe, RCSB

List of PDB id codes
4NSC, 4NSD

Identifiers

MICU1 ; CALC; CBARA1; EFHA3; MPXPS

External IDs

OMIM: 605084 MGI: 2384909 HomoloGene: 4431 GeneCards: MICU1 Gene

Gene ontology
Molecular function	• calcium ion binding • protein binding • protein heterodimerization activity
Cellular component	• intracellular • mitochondrial inner membrane • mitochondrial intermembrane space • integral component of mitochondrial membrane • calcium channel complex • uniplex complex
Biological process	• mitochondrial calcium ion transport • defense response • calcium ion import into mitochondrion • protein homooligomerization • mitochondrial calcium ion homeostasis • positive regulation of mitochondrial calcium ion concentration • calcium ion import
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000107745

ENSMUSG00000020111

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 10:
74.13 – 74.39 Mb

Chr 10:
59.7 – 59.86 Mb

PubMed search

Calcium-binding atopy-related autoantigen 1 is a protein that in humans is encoded by the CBARA1 gene.^[1]^[2]

References

↑ Natter S, Seiberler S, Hufnagl P, Binder BR, Hirschl AM, Ring J, Abeck D, Schmidt T, Valent P, Valenta R (Nov 1998). "Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients". FASEB J 12 (14): 1559–69. PMID 9806765.
↑ "Entrez Gene: CBARA1 calcium binding atopy-related autoantigen 1".

Further reading

Kimura K, Wakamatsu A, Suzuki Y et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Wiemann S, Weil B, Wellenreuther R et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

External links

MICU1 human gene location in the UCSC Genome Browser.
MICU1 human gene details in the UCSC Genome Browser.