CA10

Carbonic anhydrase X
Identifiers
SymbolsCA10 ; CA-RPX; CARPX; HUCEP-15
External IDsOMIM: 604642 MGI: 1919855 HomoloGene: 23201 ChEMBL: 4645 GeneCards: CA10 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez5693472605
EnsemblENSG00000154975ENSMUSG00000056158
UniProtQ9NS85P61215
RefSeq (mRNA)NM_001082533NM_028296
RefSeq (protein)NP_001076002NP_082572
Location (UCSC)Chr 17:
49.71 – 50.24 Mb
Chr 11:
93.1 – 93.6 Mb
PubMed search

Carbonic anhydrase-related protein 10 is an enzyme that in humans is encoded by the CA10 gene.[1][2][3]

This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene.[3]

References

  1. Hewett-Emmett D, Tashian RE (Aug 1996). "Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families". Mol Phylogenet Evol 5 (1): 50–77. doi:10.1006/mpev.1996.0006. PMID 8673298.
  2. Kleiderlein JJ, Nisson PE, Jessee J, Li WB, Becker KG, Derby ML, Ross CA, Margolis RL (Feb 1999). "CCG repeats in cDNAs from human brain". Hum Genet 103 (6): 666–73. doi:10.1007/s004390050889. PMID 9921901.
  3. 3.0 3.1 "Entrez Gene: CA10 carbonic anhydrase X".

Further reading