Bucetin
Bucetin|
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| Systematic (IUPAC) name |
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N-(4-Ethoxyphenyl)-3-hydroxybutanamide |
| Clinical data |
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| Identifiers |
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N02BE04 |
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| PubChem |
CID 14130 |
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| ChemSpider |
13507 |
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| ChEMBL |
CHEMBL1697856 |
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| Chemical data |
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| Formula |
C12H17NO3 |
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223.268 g/mol |
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SMILES
- O=C(Nc1ccc(OCC)cc1)CC(O)C
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InChI=1S/C12H17NO3/c1-3-16-11-6-4-10(5-7-11)13-12(15)8-9(2)14/h4-7,9,14H,3,8H2,1-2H3,(H,13,15)
Key:LIAWQASKBFCRNR-UHFFFAOYSA-N
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Bucetin is a pharmaceutical drug that acts as an analgesic and antipyretic.[1] Chemically, it is similar to phenacetin with which it shares the risk of carcinogenesis.[2] Bucetin was withdrawn from use in 1986 due to renal toxicity.[3]
See also
References
- ↑ "WHOCC - ATC/DDD Index". WHO Collaborating Centre for Drug Statistics Methodology. December 19, 2013.
- ↑ Togei, K; Sano, N; Maeda, T; Shibata, M; Otsuka, H (1987). "Carcinogenicity of bucetin in (C57BL/6 X C3H)F1 mice". Journal of the National Cancer Institute 79 (5): 1151–8. doi:10.1093/jnci/79.5.1151. PMID 3479641.
- ↑ Fung, M.; Thornton, A.; Mybeck, K.; Wu, J. H.-h.; Hornbuckle, K.; Muniz, E. (2001). "Evaluation of the Characteristics of Safety Withdrawal of Prescription Drugs from Worldwide Pharmaceutical Markets-1960 to 1999". Drug Information Journal 35: 293–317. doi:10.1177/009286150103500134.
Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA) |
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| Pyrazolones /
Pyrazolidines | |
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| | Salicylates | |
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| Acetic acid derivatives
and related substances | |
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| | Oxicams | |
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| Propionic acid derivatives
(profens) | |
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| N-Arylanthranilic acids
(fenamates) | |
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| | Coxibs | |
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| | Other | |
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| | | |
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| | Description |
- Anatomy
- head
- neck
- arms
- chest and back
- diaphragm
- abdomen
- genital area
- legs
- Muscle tissue
- Physiology
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| | Disease |
- Myopathy
- Soft tissue
- Connective tissue
- Congenital
- abdomen
- muscular dystrophy
- Neoplasms and cancer
- Injury
- Symptoms and signs
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| | Treatment |
- Procedures
- Drugs
- anti-inflammatory
- muscle relaxants
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Look up bucetin in Wiktionary, the free dictionary. |
