Brigitta Stockinger

Gitta Stockinger
Born Brigitta Stockinger
Fields
Institutions
Alma mater University of Mainz (PhD)
Notable awards
Website
www.nimr.mrc.ac.uk/research/gitta-stockinger

Brigitta Stockinger, FMedSci, FRS, is a molecular immunologist and Head of the Medical Research Council Division of molecular Immunology. Stockinger's research has contributed insights into the regulation and maintenance of peripheral T cell immune responses.[1][2][3][4][5][6][7][8][9][10]

Education

Stockinger was educated at the University of Mainz where she was awarded a PhD in Biology.

Career

Awards and honours

Stockinger was elected a Fellow of the Royal Society in 2013, her nomation reads:

“ Brigitta Stockinger has contributed insights regulation and maintenance of peripheral T cell immune responses. She was the first to define mechanisms underlying the differentiation of Th17 cells and demonstrated substantial pasticity in TH17 cell function depending on the inflammatory environment. Stockinger identified the Aryl hydrocarbon receptor (AhR) as connector between the immune system and environmental stimuli, showing that it shapes the functional differentiation of Th17 effector cells. The AhR links their role in host defense as well as their role in autoimmunity to environmental factors. Research into the physiological roles of AhR in the immune system beyond its role in toxicology provides a major breakthrough for both disciplines.[11] ”

In 2008, she was elected a member of European Molecular Biology Organization (EMBO).

References

  1. ↑ Veldhoen, M.; Hirota, K.; Westendorf, A. M.; Buer, J.; Dumoutier, L.; Renauld, J. C.; Stockinger, B. (2008). "The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins". Nature 453 (7191): 106. doi:10.1038/nature06881.
  2. ↑ Veldhoen, M.; Uyttenhove, C.; Van Snick, J.; Helmby, H.; Westendorf, A.; Buer, J.; Martin, B.; Wilhelm, C.; Stockinger, B. (2008). "Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset". Nature Immunology 9 (12): 1341. doi:10.1038/ni.1659.
  3. ↑ Veldhoen, M; Hocking, R. J.; Atkins, C. J.; Locksley, R. M.; Stockinger, B (2006). "TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells". Immunity 24 (2): 179–89. doi:10.1016/j.immuni.2006.01.001. PMID 16473830.
  4. ↑ Stockinger, B. (2013). "Open questions: A few that need answers in immunology". BMC Biology 11: 115. doi:10.1186/1741-7007-11-115.
  5. ↑ List of publications from Microsoft Academic Search
  6. ↑ Brigitta Stockinger's publications indexed by the Scopus bibliographic database, a service provided by Elsevier.
  7. ↑ Vieira, P. L.; Christensen, J. R.; Minaee, S; O'Neill, E. J.; Barrat, F. J.; Boonstra, A; Barthlott, T; Stockinger, B; Wraith, D. C.; O'Garra, A (2004). "IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells". Journal of immunology (Baltimore, Md. : 1950) 172 (10): 5986–93. doi:10.4049/jimmunol.172.10.5986. PMID 15128781.
  8. ↑ Stockinger, B.; Veldhoen, M. (2007). "Differentiation and function of Th17 T cells". Current Opinion in Immunology 19 (3): 281–6. doi:10.1016/j.coi.2007.04.005. PMID 17433650.
  9. ↑ Buckley, C. D.; Gilroy, D. W.; Serhan, C. N.; Stockinger, B.; Tak, P. P. (2012). "The resolution of inflammation". Nature Reviews Immunology 13: 59. doi:10.1038/nri3362.
  10. ↑ Stockinger, B; Zal, T; Zal, A; Gray, D (1996). "B cells solicit their own help from T cells". The Journal of experimental medicine 183 (3): 891–9. doi:10.1084/jem.183.3.891. PMC 2192359. PMID 8642293.
  11. ↑ http://royalsociety.org/people/brigitta-stockinger/