Bone morphogenetic protein 8A
| Bone morphogenetic protein 8a | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | BMP8A ; FLJ14351; FLJ45264 | ||||||||||||
| External IDs | MGI: 104515 HomoloGene: 130471 GeneCards: BMP8A Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 353500 | 12163 | |||||||||||
| Ensembl | ENSG00000183682 | ENSMUSG00000032726 | |||||||||||
| UniProt | Q7Z5Y6 | P34821 | |||||||||||
| RefSeq (mRNA) | NM_181809 | NM_001256019.1 | |||||||||||
| RefSeq (protein) | NP_861525 | NP_001242948.1 | |||||||||||
| Location (UCSC) | Chr 1: 39.96 – 39.99 Mb | Chr 4: 122.99 – 123.02 Mb | |||||||||||
| PubMed search | |||||||||||||
Bone morphogenetic protein 8A (BMP8A) is a protein that in humans is encoded by the BMP8A gene.[1]
BMP8A is a polypeptide member of the TGFβ superfamily of proteins. It, like other bone morphogenetic proteins (BMPs), is involved in the development of bone and cartilage. BMP8A may be involved in epithelial osteogenesis. It also plays a role in bone homeostasis. It is a disulfide-linked homodimer.
References
Further reading
- Davila S, Froeling FE, Tan A et al. (2010). "New genetic associations detected in a host response study to hepatitis B vaccine.". Genes Immun. 11 (3): 232–8. doi:10.1038/gene.2010.1. PMID 20237496.
- Strausberg RL, Feingold EA, Grouse LH et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gregory SG, Barlow KF, McLay KE et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
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