Bisindolylmaleimide

Bisindolylmaleimide
Names

IUPAC name 3,4-Di(1H-indol-2-yl)-1H-pyrrole-2,5-dione
Identifiers
ChemSpider	8862983
InChI InChI=1S/C20H13N3O2/c24-19-17(15-9-11-5-1-3-7-13(11)21-15)18(20(25)23-19)16-10-12-6-2-4-8-14(12)22-16/h1-10,21-22H,(H,23,24,25) Key: LRBHDUWDZCAYDA-UHFFFAOYSA-N InChI=1/C20H13N3O2/c24-19-17(15-9-11-5-1-3-7-13(11)21-15)18(20(25)23-19)16-10-12-6-2-4-8-14(12)22-16/h1-10,21-22H,(H,23,24,25) Key: LRBHDUWDZCAYDA-UHFFFAOYAH
Jmol-3D images	Image
PubChem	10687637
SMILES O=C5C(\c2cc1ccccc1n2)=C(\c4cc3ccccc3n4)C(=O)N5
Properties
Molecular formula	C₂₀H₁₃N₃O₂
Molar mass	327.34 g·mol⁻¹
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Bisindolylmaleimide is an organic compound that forms the core chemical structure of a variety of biologically active compounds.^[1]

Examples of bisindolylmaleimide derivatives include:

Bisindolylmaleimide I
Enzastaurin
Ruboxistaurin
Tivantinib

References

↑ Faul, Margaret M.; Winneroski, Leonard L.; Krumrich, Christine A. (1998). "A New, Efficient Method for the Synthesis of Bisindolylmaleimides". The Journal of Organic Chemistry 63 (17): 6053. doi:10.1021/jo980513c. PMID 11672217.

External links

Media related to Bisindolylmaleimides at Wikimedia Commons